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O&G TopicsGynaecological oncology — survivorship

O&G · Gynaecological oncology — survivorship

Survivorship, MDT working and the generalist's role — surveillance schedules, late effects and transition to shared care

Also known as Cancer survivorship · Gynae-oncology survivorship · Post-treatment surveillance · Survivorship care plan · Shared care after gynae cancer · Fear of cancer recurrence · Late effects of gynaecological cancer treatment

Exam-exhaustive FRANZCOG fellowship reference on gynaecological cancer survivorship written for the generalist: surveillance schedules by cancer type (endometrial, ovarian, cervical) with visit intervals and the role of vault cytology, CA-125 and imaging; the four dominant late effects (lymphoedema, sexual dysfunction, premature menopause, psychosocial distress and fear of recurrence); the GP and generalist O&G role in the shared-care transition; the written survivorship care plan; and return to work. Surveillance is symptom-driven, not test-driven. ANZ-primary, globally tagged to MRCOG, ABOG, FRCSC and MRCPI.

medium12 referencesUpdated 28 July 202612 min readVerification in progress

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Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • A swollen leg after pelvic radiotherapy is lymphoedema until proven otherwise — but recurrent disease must always be excluded with targeted imaging
  • Sexual dysfunction affects more than 60 per cent of gynae-cancer survivors yet is rarely volunteered — the clinician must raise it at every visit
  • Treatment-induced premature menopause in a young woman is lost to follow-up too often — bone-density and cardiovascular monitoring is lifelong
  • Fear of cancer recurrence that is intrusive, persistent and disabling is clinical, not normal adjustment — refer to psycho-oncology
  • Routine vault cytology, CA-125 and imaging add no survival benefit in the asymptomatic woman — symptom-prompted review detects most recurrences
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Your progress

Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • A swollen leg after pelvic radiotherapy is lymphoedema until proven otherwise — but recurrent disease must always be excluded with targeted imaging
  • Sexual dysfunction affects more than 60 per cent of gynae-cancer survivors yet is rarely volunteered — the clinician must raise it at every visit
  • Treatment-induced premature menopause in a young woman is lost to follow-up too often — bone-density and cardiovascular monitoring is lifelong
  • Fear of cancer recurrence that is intrusive, persistent and disabling is clinical, not normal adjustment — refer to psycho-oncology
  • Routine vault cytology, CA-125 and imaging add no survival benefit in the asymptomatic woman — symptom-prompted review detects most recurrences
One-line fellowship answer

Gynaecological cancer survivorship begins at diagnosis and continues for life. Surveillance is symptom-driven, not test-driven — thorough history and examination detect most recurrences, and routine vault cytology, CA-125 and imaging add no survival benefit in the asymptomatic woman. The generalist anchors the long-term phase with a written survivorship care plan: cancer history, treatments received, the surveillance schedule, late-effect monitoring (lymphoedema, sexual dysfunction, premature menopause, fear of recurrence), GP responsibilities, and red flags for re-presentation.[1][2][3]

A 58-year-old woman sits in your general gynaecology clinic two years after a radical hysterectomy and pelvic radiotherapy for stage IIB cervical cancer. Her oncology team has signed her off to "shared care." She has a swollen left leg she has not mentioned, pain with intercourse she is too embarrassed to name, hot flushes from abrupt menopause, and a quiet, daily terror that the cancer is coming back. She is every gynae-oncology survivor — and she is now your patient. This topic teaches the generalist O&G how to run that long phase well.[2][6]

Overview — survivorship is a phase, not an afterthought

Cancer survivorship, in the consensus sense, spans from the moment of diagnosis through the balance of life, encompassing physical, psychosocial, and existential health. It is not what happens after treatment ends — it is a restructuring of care that begins at diagnosis and runs in parallel with active treatment, then takes over as the dominant mode once curative-intent therapy is complete.[2][3]

The GCIG long-term survivorship position paper (Woopen et al 2022) defines a long-term survivor as a woman at least five years from diagnosis, irrespective of recurrence. Most gynae-cancer survivors reach this milestone: endometrial cancer has an all-stage five-year survival of roughly 80 per cent, cervical 60 to 70 per cent, and ovarian 30 to 50 per cent. Survival is disproportionately good relative to incidence — gynaecological cancers are about 12 per cent of new cancers in women but about 15 per cent of female cancer survivors. The survivor cohort is large, growing, and increasingly yours.[2]

The survivorship numbers a candidate must know

~80%Endometrial cancer 5-yr survivalall-stage; the largest survivor cohort
60-70%Cervical cancer 5-yr survivalall-stage
Over 50%Survivors reporting a late effectGCIG 2022 — most have an unmet need
Over 60%Sexual dysfunction after gynae cancerrarely volunteered — you must ask
[2] [6]

The survivorship phases

Survivorship has three recognised phases that the generalist must navigate:[2]

  • Acute survival — diagnosis through the end of active treatment. The oncology MDT leads; the generalist supports comorbidity, acute effects, and the woman's psychosocial needs.
  • Extended survival — the transition. Active treatment ends; the woman moves from specialist-dominated surveillance toward shared care. This is where the survivorship care plan is handed over and where most survivors are lost to late-effect monitoring.
  • Permanent survival (long-term re-entry) — years out, the woman is back in the community. Late effects accumulate over decades; follow-up should be offered lifelong in a shared-care model.[2]
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References12ShowHide
  1. [1]Salani R, Khanna N, Frimer M, et al. An update on post-treatment surveillance and diagnosis of recurrence in women with gynecologic malignancies: Society of Gynecologic Oncology (SGO) recommendations. Gynecol Oncol, 2017.PMID 28372871
  2. [2]Woopen H, Sehouli J, Davis A, et al. GCIG-Consensus guideline for Long-term survivorship in gynecologic Cancer: A position paper from the gynecologic cancer Intergroup (GCIG) symptom benefit committee. Cancer Treat Rev, 2022.PMID 35525106
  3. [3]Mayer DK, Nekhlyudov L, Snyder CF, et al. American Society of Clinical Oncology clinical expert statement on cancer survivorship care planning. J Oncol Pract, 2014.PMID 25316025
  4. [4]Maheu C, Lebel S, Bernstein LJ, et al. Fear of cancer recurrence therapy (FORT): A randomized controlled trial. Health Psychol, 2023.PMID 36862474
  5. [5]Biglia N, Zanfagnin V, Daniele A, et al. Lower Body Lymphedema in Patients with Gynecologic Cancer. Anticancer Res, 2017.PMID 28739682
  6. [6]Rizzuto I, Oehler MK, Lalondrelle S, et al. Sexual and Psychosexual Consequences of Treatment for Gynaecological Cancers. Clin Oncol (R Coll Radiol), 2021.PMID 34281725
  7. [7]Mayer DK, Green M, Check DK, et al. Is there a role for survivorship care plans in advanced cancer? Support Care Cancer, 2015.PMID 25559037
  8. [8]Panay N, Anderson RA, Nappi RE, et al. Evidence-based guideline: premature ovarian insufficiency. Hum Reprod Open, 2024.PMID 39660328
  9. [9]Hall DL, Wagner LI, Lebel S, et al. Guidelines needed for the management of fear of cancer recurrence in adult survivors of cancer in the United States: A consensus statement. Cancer, 2024.PMID 38630904
  10. [10]Rustin GJ, et al. Follow-up with CA125 after primary therapy of advanced ovarian cancer has major implications for treatment outcome and trial performances and should not be routinely performed. Ann Oncol, 2011.PMID 22180399
  11. [11]de Haan J, Verheecke M, Van Calsteren K, et al. Oncological management and obstetric and neonatal outcomes for women diagnosed with cancer during pregnancy: a 20-year international cohort study of 1170 patients. Lancet Oncol, 2018.PMID 29395867
  12. [12]Frey Tirri B, Häusermann P, Bertz H, et al. Clinical guidelines for gynecologic care after hematopoietic SCT. Report from the international consensus project on clinical practice in chronic GVHD. Bone Marrow Transplant, 2015.PMID 25347009

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