ICU · Toxicology

Lithium Toxicity

Also known as Lithium poisoning · Lithium toxicity · SILENT · Nephrogenic diabetes insipidus lithium · Whole bowel irrigation

The lithium toxicity — the narrow therapeutic index (the therapeutic 0.6 to 1.2 mmol/L), the renal clearance (the handled like the sodium), and the no antidote. The acute overdose (the early GI, the delayed neuro) versus the chronic toxicity (the neuro-dominant, the more dangerous — the tremor, the hyperreflexia, the ataxia, the seizures, the coma, the SILENT). The charcoal the not-bind; the whole-bowel irrigation for the sustained-release; the normal saline (the restore the GFR, the NOT the diuretics); the haemodialysis for the severe (with the rebound).

Checked against its sources on 14 Oct 2026