ICU · Airway management
Airway Management
Also known as Endotracheal intubation · Rapid sequence induction (RSI) · Difficult airway · Front-of-neck access (FONA)
Tracheal intubation in the critically ill patient is one of the highest-risk procedures in intensive care: the INTUBE study of nearly 3000 intubations across 29 countries found that 45.2% of patients suffered a major adverse peri-intubation event, led by cardiovascular instability. Unlike the fasted, monitored anaesthetic patient, the ICU patient is hypoxaemic, hypotensive, often shocked, and frequently difficult — so the airway is managed not as an isolated technical act but as a physiological resuscitation around a planned procedure. This topic covers airway assessment (MACOCHA, LEMON), the physiology of preoxygenation and desaturation, rapid sequence induction and its pharmacology, the Difficult Airway Society 2015 algorithm (Plans A to D), rescue oxygenation with supraglottic airways and face-mask ventilation, the cannot-intubate-cannot-oxygenate emergency and front-of-neck access, cardiovascular collapse and its prevention, capnographic monitoring, and extubation — built on the verified landmark trials and the DAS/NAP4 evidence.
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Red flags
- Peri-intubation cardiovascular collapse is the commonest major complication (42.6% in INTUBE) and the most lethal — resuscitate first: correct hypovolaemia, start or increase vasopressors, and reduce or avoid the induction dose before you push the induction agent. A patient intubated in uncorrected shock arrests on the syringe
- A low preoxygenation reserve means rapid desaturation — the critically ill patient desaturates within one or two minutes, not the eight minutes of a fasted healthy adult. Preoxygenate to an SpO2 of 100% where possible and use apnoeic oxygenation; never begin laryngoscopy on a patient who is already hypoxaemic
- Capnography is mandatory — the misplaced tube remains a leading cause of airway death (NAP4). Confirm tracheal placement with a sustained waveform of exhaled carbon dioxide on every intubation, not by chest movement or condensation alone
- A MACOCHA score of 3 or above predicts difficult intubation (validation NPV 98%) — assess every ICU patient before induction, prepare the difficult-airway kit, and call senior help early rather than after the first attempt fails
- Cannot intubate, cannot oxygenate is a time-critical emergency — if face-mask ventilation and a supraglottic airway both fail and oxygenation is being lost, perform emergency front-of-neck access (scalpel-bougie cricothyroidotomy) without delay; repeated fruitless attempts kill the patient
Meet the patient
A 66-year-old woman with severe pneumonia and septic shock — SpO2 89 percent on 15 L/min, MAP 58 on noradrenaline, GCS 12 and tiring — needs intubating. She is obese with a short neck and an overbite. Every physiological reserve is gone before you reach for the laryngoscope.[2]
The question the examiner is really asking is not "can you pass the tube" but did you resuscitate, preoxygenate and predict difficulty before you induced?[1]
References22ShowHide
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