ICU · Obstetrics
Critical illness in pregnancy: ICU management and obstetric emergencies
Also known as Pregnancy in ICU · Maternal ICU · Obstetric critical care · Peripartum ICU · Maternal mortality
Critical illness in pregnancy: physiological adaptations of pregnancy alter drug dosing, ventilation, circulation. Key changes: increased cardiac output (+30-40%), decreased SVR, increased blood volume, decreased albumin, dilutional anaemia, elevated diaphragm (decreased FRC), increased clotting factors (hypercoagulable). Common ICU indications: severe pre-eclampsia/eclampsia, HELLP, peripartum cardiomyopathy, amniotic fluid embolism, sepsis (pyelonephritis, chorioamnionitis), trauma, asthma, diabetic emergencies. Position: LEFT LATERAL tilt (avoid aortocaval compression from gravid uterus — especially after 20 weeks). Drugs: avoid ACEi/ARB, NSAIDs (3rd trimester), aminoglycosides, warfarin (teratogenic). Fetal monitoring.
Checked against its sources on 3 Sept 2026
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Red flags
- Aortocaval compression (supine, >20 weeks) — LEFT lateral tilt to relieve
- Eclamptic seizure — magnesium sulphate (loading 4g, infusion 1-2g/h)
- Amniotic fluid embolism — sudden cardiovascular collapse, coagulopathy, ARDS, high mortality
- Peripartum cardiomyopathy — heart failure in last month of pregnancy to 5 months postpartum
- HELLP syndrome — haemolysis, elevated liver enzymes, low platelets — delivery indicated
Meet the patient
A 32-year-old at 34 weeks is in septic shock from pneumonia: HR 128, BP 84 over 50, SpO2 88 percent on 15 L, lactate 3.8, with fetal tachycardia on the CTG. Before you reach for a single drug or tube, two facts reframe everything: she desaturates in 2 to 3 minutes on apnoea, and a pressure of 120 over 80 in pregnancy may already be hypertension.[1]
The two questions that decide every critically ill pregnant patient are: is the gravid uterus compressing her vena cava? (after 20 weeks, yes — tilt her left) and is this a disease delivery will cure? (pre-eclampsia, HELLP, AFE, chorioamnionitis — usually yes; pneumonia, DKA, trauma — no). Hold those two and the physiology, the drugs and the delivery decision all slot into place.[1]
References40ShowHide
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