ICU · Obs/Gynae
Obstetric emergencies in the ICU
Also known as Pre-eclampsia and eclampsia · HELLP syndrome · Peripartum cardiomyopathy · Amniotic fluid embolism · Sepsis in pregnancy · Postpartum haemorrhage in ICU · Venous thromboembolism in pregnancy · Maternal critical care · Massive obstetric haemorrhage · Pregnancy physiology and ICU implications
Obstetric ICU admissions are rare but high-stakes. Pre-eclampsia/eclampsia: magnesium sulphate for seizure prophylaxis and treatment (4 g IV load, 1-2 g/h; beats diazepam and phenytoin), antihypertensive therapy for severe-range BP (over 160/110), delivery definitive. HELLP syndrome (Haemolysis, Elevated Liver enzymes, Low Platelets): usually preterm, malaise and right upper quadrant pain in 90 percent, hypertension may be absent. Peripartum cardiomyopathy: heart failure with LVEF under 45 percent, last month of pregnancy to 5 months postpartum — treat with pregnancy-safe HF therapy (diuretics, beta-blockers, hydralazine/nitrates, digoxin) plus bromocriptine. Amniotic fluid embolism: sudden cardiovascular collapse plus coagulopathy — high-quality CPR, early echo for right ventricular failure, 1:1:1 haemostatic resuscitation, VA-ECMO for the refractory. Physiological changes of pregnancy alter drug dosing, ventilation, and fluid management.
Checked against its sources on 1 Sept 2026
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- Eclampsia: magnesium sulphate FIRST (seizures), THEN BP control. Magnesium prevents and treats seizures
- HELLP with right upper quadrant pain (90 percent of cases): check platelets and liver enzymes whatever the blood pressure
- Amniotic fluid embolism: sudden cardiovascular collapse + coagulopathy during labour or delivery — catastrophic
- Pregnant patients desaturate rapidly: reduced functional reserve from a lower FRC — pre-oxygenate 3 minutes before any intubation
Meet the patient
A 32-year-old woman at 36 weeks is admitted to ICU post-ictal, BP 172 over 114, proteinuria 3 plus, platelets 85, AST 95, LDH 650. She has just fitted in front of the midwife. The two questions that decide her next hour are the two that decide almost every obstetric emergency: is the airway and circulation safe? and what do I deliver, and when?[20]
Hold those two questions and the rest slots into place — magnesium first, severe-range blood pressure second, left-lateral tilt always, delivery definitive. Desaturation and aortocaval compression are the two physiology traps that quietly undermine the resuscitation while you reach for the next drug.[25][29]
References39ShowHide
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