ICU · Neurocritical care / vascular
Intracerebral Haemorrhage — ICH Score, BP Control & Surgery
Also known as Intracerebral haemorrhage · ICH · Intraparenchymal haemorrhage · Hypertensive haemorrhage · Amyloid angiopathy · ICH score · Haematoma expansion · Spot sign · INTERACT2 · STICH II
Intracerebral haemorrhage (ICH) is the bleeding into the brain parenchyma, most commonly from hypertension (the deep location — basal ganglia, thalamus, pons, cerebellum) or amyloid angiopathy (the lobar location in the elderly). The CT shows a hyperdense lesion. The ICH Score (the GCS, the age over 80, the infratentorial location, the volume over 30 mL, the intraventricular extension) predicts the 30-day mortality. The management: BP control to SBP 140 mmHg (the INTERACT2 trial — safe and improves the functional outcome; the IV labetalol or nicardipine), reverse the anticoagulation rapidly (the PCC for warfarin; the andexanet alfa for the DOAC; the idarucizumab for dabigatran), prevent the haematoma expansion (the spot sign on the CT angiogram predicts the expansion), and surgery (the cerebellar haemorrhage — the urgent evacuation; the supratentorial — the STICH II showed no routine benefit).
Checked against its sources on 13 Oct 2026
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A 68-year-old hypertensive man on apixaban for atrial fibrillation arrives with sudden left-sided weakness, vomiting and a GCS of 10. The CT shows a 45 mL right putaminal haematoma with intraventricular blood and early midline shift; his SBP is 198 over 112.[1]
Two questions decide his next hour, and they decide every ICH: can I drop the SBP to 140 within an hour? and can I reverse the apixaban within an hour? Hold those two and the whole topic slots into place.[1]
References23ShowHide
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- [13]Mendelow AD, Gregson BA, Fernandes HM, et al Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial Lancet, 2005.PMID 15680453
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- [18]Ma L, Hu X, Song L, et al The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial Lancet, 2023.PMID 37245517
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- [23]Hypertonic saline versus other intracranial pressure-lowering agents for people with acute traumatic brain injury Cochrane Database Syst Rev, 2020.PMID 31978260