ICU · Neurocritical care / monitoring
ICP Monitoring & Waveforms
Also known as Intracranial pressure monitoring · ICP monitoring · ICP waveforms · Lundberg waves · Plateau waves · A-waves · P1 P2 P3 · External ventricular drain · EVD · Intraparenchymal pressure monitor · Codman · Cerebral perfusion pressure · CPP
Intracranial pressure (ICP) monitoring measures the pressure within the skull, guiding the management of raised ICP (target under 22 mmHg in TBI). The cerebral perfusion pressure (CPP = MAP minus ICP) is the key derived variable, with a target of 60-70 mmHg. The intraventricular catheter (external ventricular drain) is the gold standard (it measures, drains, and samples the CSF); the intraparenchymal microsensor (Codman) is accurate but cannot drain. The normal ICP waveform has three peaks: P1 (the arterial percussion), P2 (the tidal wave reflecting compliance — a P2 rising above P1 indicates a loss of compliance), and P3 (the venous dicrotic). The Lundberg A-wave (the plateau wave — a sudden sustained plateau rise from a vasodilatory cascade) indicates a critical loss of the intracranial compliance and requires an urgent treatment.
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A 24-year-old man is in neurocritical care 36 hours after a severe traumatic brain injury (GCS 5 at the scene). He has an external ventricular drain and an intraparenchymal bolt in situ. The ICP has been steady at 16 mmHg with a CPP of 65, the trace showing a crisp P1 above P2.[1]
At 3 am the ICP alarm fires: the number is 45 mmHg, the trace has flattened into a plateau, and his right pupil has blown to 6 mm. Two questions now decide everything — is there a surgical lesion to evacuate, and is the brain on the steep part of its compliance curve? Hold those two and the whole escalation staircase slots into place.[1]
References18ShowHide
- [1]Carney N, Totten AM, O'Reilly C, Ullman JS, Hawryluk GWJ, Bell MJ, Bratton SL, Chesnut R, Harris OA, Kissoon N, Rubiano AM, Shutter L, Tasker RC, Vavilala MS, Wilberger J, Wright DW, Ghajar J. Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition Neurosurgery, 2017.PMID 27654000
- [2]Hutchinson PJ, Kolias AG, Timofeev IS, Corteen EA, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ; RESCUEicp Trial Collaborators. Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension N Engl J Med, 2016.PMID 27602507
- [3]Chesnut RM, Temkin N, Carney N, Dikmen S, Rondina C, Videtta W, Petroni G, Lujan S, Pridgeon J, Barber J, Machamer J, Chaddock K, Celix JM, Cherner M, Hendrix T; Global Neurotrauma Research Group. A trial of intracranial-pressure monitoring in traumatic brain injury N Engl J Med, 2012.PMID 23234472
- [4]Chesnut RM, Marshall LF, Klauber MR, Blunt BA, Baldwin N, Eisenberg HM, Jane JA, Marmarou A, Foulkes MA. The role of secondary brain injury in determining outcome from severe head injury J Trauma, 1993.PMID 8459458
- [5]Lundberg N. Continuous recording of the ventricular-fluid pressure in patients with severe acute traumatic brain injury. A preliminary report J Neurosurg, 1965.PMID 5832775
- [6]Czosnyka M, Smielewski P, Kirkpatrick P, et al. Monitoring of cerebral autoregulation in head-injured patients Stroke, 1996.PMID 8841340
- [7]Czosnyka M, Brady K, Reinhard M, Smielewski P, Steiner LA. Monitoring of cerebrovascular autoregulation: facts, myths, and missing links Neurocrit Care, 2009.PMID 19127448
- [8]Cnossen MC, Huijben JA, van der Jagt M, et al. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study Crit Care, 2017.PMID 28874206
- [9]Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, Pickard JD. Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury Crit Care Med, 2002.PMID 11940737
- [10]Sorrentino E, Diedler J, Kasprowicz M, Budohoski KP, Haubrich C, Smielewski P, Outtrim JG, Manktelow A, Hutchinson PJ, Pickard JD, Menon DK, Czosnyka M. Critical thresholds for cerebrovascular reactivity after traumatic brain injury Neurocrit Care, 2012.PMID 21964774
- [11]Robertson CS, Valadka AB, Hannay HJ, Contant CF, Gopinath SP, Cormio M, Uzura M, Grossman RG. Prevention of secondary ischemic insults after severe head injury Crit Care Med, 1999.PMID 10548187
- [12]Stein KY, Froese L, Gomez A, Sainbhi AS, Vakitbilir N, Ibrahim Y, Zeiler FA. Intracranial Pressure Monitoring and Treatment Thresholds in Acute Neural Injury: A Narrative Review of the Historical Achievements, Current State, and Future Perspectives Neurotrauma Rep, 2023.PMID 37636334
- [13]Fink ME. Osmotherapy for intracranial hypertension: mannitol versus hypertonic saline Continuum (Minneap Minn), 2012.PMID 22810253
- [15]Castellani G, Zweifel C, Kim DJ, Carrera E, Radolovich DK, Smielewski P, Hutchinson PJ, Pickard JD, Czosnyka M. Plateau waves in head injured patients requiring neurocritical care Neurocrit Care, 2009.PMID 19565359
- [16]Hawryluk GWJ, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Chesnut RM. A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC) Intensive Care Med, 2019.PMID 31659383
- [17]Schizodimos T, Soulountsi V, Iasonidou C, Kapravelos N. An overview of management of intracranial hypertension in the intensive care unit J Anesth, 2020.PMID 32440802
- [18]Kramer AH, Couillard PL, Zygun DA, Aries MJ, Gallagher CN. Continuous Assessment of "Optimal" Cerebral Perfusion Pressure in Traumatic Brain Injury: A Cohort Study of Feasibility, Reliability, and Relation to Outcome Neurocrit Care, 2019.PMID 29987688
- [19]Poca MA, Lopez-Bermeo D, Cano P, Maruccia F, Fajardo C, Delgado I, Munar F, Garcia-Merino A, Sahuquillo J. Continuous Intracranial Pressure Monitoring in Children with 'Benign' External Hydrocephalus J Clin Med, 2025.PMID 40364074