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ICU TopicsGI & nutrition / surgical

ICU · GI & nutrition / surgical

Intra-abdominal Hypertension & Abdominal Compartment Syndrome — IAP, APP & Decompression

Also known as Intra-abdominal hypertension · IAH · Abdominal compartment syndrome · ACS · Intra-abdominal pressure · IAP · Abdominal perfusion pressure · APP · WSACS · Bladder pressure · Decompressive laparotomy · Open abdomen

The intra-abdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) are the raised intra-abdominal pressure (IAP) and its consequences. The WSACS definitions: the IAP is measured via the bladder with the patient supine, instilling no more than 25 mL of saline; a normal IAP is about 5 to 7 mmHg; the IAH is a sustained IAP of 12 mmHg or more (graded I to IV); the abdominal perfusion pressure (APP) equals the MAP minus the IAP, with a mean APP under 60 mmHg marking abdominal hypoperfusion; the ACS is a sustained IAP over 20 mmHg PLUS new organ dysfunction or failure. The organ effects: reduced venous return and cardiac output with falsely high CVP, raised airway pressure, renal failure, splanchnic ischaemia, raised ICP. The primary ACS (the abdominopelvic cause) vs the secondary (the sepsis, the massive fluid resuscitation, the burns). IAH is medical; ACS is surgical — decompressive laparotomy.

high27 referencesUpdated 20 Aug 202625 min readVerification in progress

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Overview — a raised pressure, a multi-organ cascade, a surgical rescue

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Intra-abdominal hypertension (IAH) is an intra-abdominal pressure (IAP) of 12 mmHg or more; abdominal compartment syndrome (ACS) is a sustained IAP over 20 mmHg with organ dysfunction or failure — the "plus organ failure" is the sine qua non that converts a number into a syndrome.[15][19] The IAP is measured via the bladder with the patient supine, instilling a small volume of no more than 25 mL — larger instillation volumes overestimate the pressure; a normal IAP is about 5 to 7 mmHg.[21][13] The abdominal perfusion pressure (APP) equals MAP minus IAP — superior to MAP alone as a resuscitation endpoint and predictor of survival — with a mean APP under 60 mmHg marking abdominal hypoperfusion.[16][17] The organ cascade is cardiovascular (reduced venous return and cardiac output, falsely high CVP and wedge pressure), respiratory (raised airway pressures), and renal (blood flow and filtration fall to under a quarter of normal once the IAP reaches 20 mmHg).[7][22] IAH is managed medically — sedation, evacuation of luminal contents, drainage of collections, fluid stewardship, neuromuscular blockade; ACS is managed surgically with decompressive laparotomy and the open abdomen.[1][24]

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References27ShowHide
  1. [1]Kirkpatrick AW, Roberts DJ, De Waele J, et al Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome Intensive Care Med, 2013.PMID 23673399
  2. [2]Malbrain ML, De Laet IE Intra-abdominal hypertension: definitions, monitoring, interpretation and management Best Pract Res Clin Anaesthesiol, 2013.PMID 24012236
  3. [3]Malbrain ML, Chiumello D, Pelosi P, et al Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study Intensive Care Med, 2004.PMID 14758472
  4. [4]Cheatham ML, Safcsak K Is the evolving management of intra-abdominal hypertension and abdominal compartment syndrome improving survival? Crit Care Med, 2010.PMID 20095067
  5. [5]Cheatham ML, Safcsak K Percutaneous catheter decompression in the treatment of elevated intraabdominal pressure Chest, 2011.PMID 21903735
  6. [6]Ouellet JF, Leppaniemi A, Ball CG, et al. Alternatives to formal abdominal decompression Am Surg, 2011.PMID 21944453
  7. [7]Malbrain ML, Ameloot K, Gillebert C, et al. Cardiopulmonary monitoring in intra-abdominal hypertension Am Surg, 2011.PMID 21944448
  8. [8]Björck M, Wanhainen A Management of abdominal compartment syndrome and the open abdomen Eur J Vasc Endovasc Surg, 2014.PMID 24447530
  9. [9]Jacobs R, Wise R, Malbrain MLNG Fluid Management, Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome: A Narrative Review Life (Basel), 2022.PMID 36143427
  10. [10]Padar M, Reintam Blaser A, Talving P, Starkopf L, Starkopf J Abdominal Compartment Syndrome: Improving Outcomes With A Multidisciplinary Approach - A Narrative Review J Multidiscip Healthc, 2019.PMID 31908470
  11. [11]Cheatham ML, De Waele JJ, De Laet I, et al The impact of body position on intra-abdominal pressure measurement: a multicenter analysis Crit Care Med, 2009.PMID 19487946
  12. [12]Strang SG, Van Lieshout EM, Breederveld RS, et al. A systematic review on intra-abdominal pressure in severely burned patients Burns, 2014.PMID 24050978
  13. [13]Malbrain ML, Deeren DH Effect of bladder volume on measured intravesical pressure: a prospective cohort study Crit Care, 2006.PMID 16934130
  14. [14]Kirkpatrick AW, Roberts DJ, Jaeschke R, et al. Methodological background and strategy for the 2012-2013 updated consensus definitions and clinical practice guidelines from the abdominal compartment society Anaesthesiol Intensive Ther, 2015.PMID 26588481
  15. [15]Malbrain ML, Cheatham ML, Kirkpatrick A, et al Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions Intensive Care Med, 2006.PMID 16967294
  16. [16]Cheatham ML, White MW, Sagraves SG, et al Abdominal perfusion pressure: a superior parameter in the assessment of intra-abdominal hypertension J Trauma, 2000.PMID 11038078
  17. [17]Al-Dorzi HM, Tamim HM, Rishu AH, et al Intra-abdominal pressure and abdominal perfusion pressure in cirrhotic patients with septic shock Ann Intensive Care, 2012.PMID 22873420
  18. [18]Özkarakaş H, Tekgül ZT, Arslan M, et al Does Maintaining a Targeted Abdominal Perfusion Pressure Reduce Renal Damage in Patients with Septic Shock?: A Randomized, Controlled, and Open-label Study Balkan Med J, 2023.PMID 37721127
  19. [19]Lee AHH, Lee WS, Anderson D Severe pancreatitis complicated by abdominal compartment syndrome managed with decompressive laparotomy: a case report BMC Surg, 2019.PMID 31419970
  20. [20]Reintam Blaser A, Regli A, De Keulenaer B, et al Incidence, Risk Factors, and Outcomes of Intra-abdominal Hypertension in Critically Ill Patients-A Prospective Multicenter Study (IROI Study) Crit Care Med, 2019.PMID 30608280
  21. [21]De Keulenaer BL, De Waele JJ, Powell B, et al What is normal intra-abdominal pressure and how is it affected by positioning, body mass and positive end-expiratory pressure? Intensive Care Med, 2009.PMID 19242675
  22. [22]Harman PK, Kron IL, McLachlan HD, et al Elevated intra-abdominal pressure and renal function Ann Surg, 1982.PMID 7125746
  23. [23]Djavani K, Wanhainen A, Björck M Intra-abdominal hypertension and abdominal compartment syndrome following surgery for ruptured abdominal aortic aneurysm Eur J Vasc Endovasc Surg, 2006.PMID 16458547
  24. [24]De Laet I, Hoste E, Verholen E, et al The effect of neuromuscular blockers in patients with intra-abdominal hypertension Intensive Care Med, 2007.PMID 17594072
  25. [25]Chiles KT, Feeney CM Abdominal compartment syndrome successfully treated with neuromuscular blockade Indian J Anaesth, 2011.PMID 22013257
  26. [26]Depauw PRAM, Groen RJM, Van Loon J, et al The significance of intra-abdominal pressure in neurosurgery and neurological diseases: a narrative review and a conceptual proposal Acta Neurochir (Wien), 2019.PMID 30911831
  27. [27]Sakka SG [The patient with intra-abdominal hypertension]. Anasthesiol Intensivmed Notfallmed Schmerzther, 2016.PMID 26863642

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