ICU · Ethics and quality
ICU discharge planning and transition of care: failures, criteria, and systems
Also known as ICU discharge planning · Transition of care · ICU step-down · Readmission · Post-ICU syndrome · ICU follow-up clinic · SBARR handover · Medication reconciliation
ICU discharge is a high-risk transition — one of the most dangerous handovers in hospital medicine. Premature discharge → readmission (roughly 6-10% of patients discharged alive from ICU) and markedly higher mortality (24.7% vs 4.0% in-hospital mortality among readmitted vs non-readmitted patients in Cooper's 28-hospital series); delayed discharge → ICU bed-blocking, increased cost, nosocomial infection, ICU-acquired weakness, and prolonged delirium. READMISSION RISK FACTORS: respiratory (day-of-discharge hypoxaemia, hypercapnia, or complex respiratory nursing needs), neurological (day-of-discharge neurologic impairment — GCS), severity and workload (higher acute physiology score at discharge — APS over 40; longer ICU stay; deterioration on the ward before ICU admission), and OPERATIONAL (after-hours discharge 18:00-06:00 → higher readmission and mortality, adjusted OR 1.34-1.42 in ANZICS data — Gantner 2014, Pilcher 2007; UK night discharge more often judged premature — Goldfrad 2000). STRUCTURED DISCHARGE PLANNING rests on five pillars: (1) OBJECTIVE READINESS CRITERIA — resolving organ failure, stable haemodynamics without escalating vasopressors, adequate ventilation without hypoxaemia or hypercapnia, neurologically appropriate (baseline mental state, delirium controlled). (2) PHARMACIST-LED MEDICATION RECONCILIATION — stop ICU-only drugs (sedatives, NMBA), restart held home meds (beta-blockers, statins, anticonvulsants — adjust for recovering renal/hepatic function), correct durations (antibiotics, steroid taper), avoid indefinite gastric prophylaxis. (3) STRUCTURED HANDOVER — SBARR (Situation, Background, Assessment, Recommendation, Read-back) or ISBAR, written + verbal, with explicit acceptance of care by the receiving team. (4) TIMING — discharge in daytime (ideally before 16:00, before 18:00 at latest), avoid night discharge; if unavoidable, enhanced handover + document rationale. (5) POST-DISCHARGE FOLLOW-UP — ICU follow-up clinic at 2-8 weeks to screen for POST-INTENSIVE CARE SYNDROME (PICS): cognitive impairment (memory, executive function, attention — affects ~30-40%, persists at 1yr in 25%), psychological morbidity (depression 30%, PTSD 20%, anxiety 40% — combined physical/cognitive/mental health impairment affects 50-70% at 1 year), and physical weakness (ICU-acquired weakness CIP/CIM 25-50%). PREVENTION of PICS: ABCDEF bundle (Assess pain, Both spontaneous awakening/breathing trials, Choice of analgesia/sedation, Delirium monitoring, Early mobility, Family engagement) — Pun 2019 ICU Liberation Collaborative (15,000+ patients) showed lower mortality, more coma-/delirium-free days, and higher discharge home. FAMILY morbidity (PICS-Family) is also common — depression, anxiety, PTSD, caregiver burden.
Practise this topic
On this page
Study tools
Your progress
Saved on this device.
Target exams
Red flags
- ICU readmission rate ~6-10% — readmitted patients carry markedly higher mortality (24.7% vs 4.0% in Cooper's series)
- Night/after-hours discharge → higher readmission and mortality (adjusted OR 1.34-1.42, ANZICS data)
- Patients on vasopressors/NIV at discharge → high readmission risk
- Post-ICU syndrome (PICS) affects 50-70% of survivors at 1yr — cognitive, psychological, physical
- Medication reconciliation errors common at discharge — pharmacist-led reconciliation targets error prevention; RCT evidence for fewer readmissions is lacking (Ceschi)
- PICS-Family: caregivers also develop depression, anxiety, PTSD, complicated grief
- Premature discharge — judged premature far more often at night (42.6% vs 5.0%) — independently associated with higher hospital mortality (Goldfrad)
- Dysphagia post-extubation in 40-60% — aspiration risk if not screened before feeding
- Continuing stress-ulcer prophylaxis and VTE prophylaxis beyond indication → harm
Meet the patient
A 68-year-old man was admitted six days ago with severe community-acquired pneumonia and septic shock. He was intubated for three days and received two days of noradrenaline. He is now extubated, on nasal specs 2 L per min with SpO2 95 percent, RR 18, afebrile, MAP 78 off all vasopressors for 48 hours, GCS 15, CAM-negative, with a bedside swallow screen showing mild dysphagia on thickened fluids. Creatinine peaked at 220 and is now 145 (baseline 120). Sputum grew Streptococcus pneumoniae. The ward bed manager is asking for ICU discharge at 19:00 because a retrieval is incoming.[16]
The two questions that decide this discharge are the two that decide every discharge: is he physiologically stable enough that the ward can hold him? and is 19:00 the wrong time to send him? The first is answered by objective discharge criteria; the second — in ANZ data — is almost always yes. Hold those two and the rest of this topic slots into place.[18][3][6]
References24ShowHide
- [1]Cooper GS, Sirio CA, Rotondi AJ, et al. Are readmissions to the intensive care unit a useful measure of hospital performance? Med Care, 1999.PMID 10213020
- [2]Ceschi A, Noseda R, Pironi M, et al. Effect of Medication Reconciliation at Hospital Admission on 30-Day Returns to Hospital: A Randomized Clinical Trial JAMA Netw Open, 2021.PMID 34529065
- [3]Pilcher DV, Duke GJ, George C, et al. After-hours discharge from intensive care increases the risk of readmission and death Anaesth Intensive Care, 2007.PMID 18020063
- [4]Elliott D, Davidson JE, Harvey MA, et al. Exploring the scope of post-intensive care syndrome therapy and care: engagement of non-critical care providers and survivors in a second stakeholders meeting Crit Care Med, 2014.PMID 25083984
- [5]Cuthbertson BH, Rattray J, Campbell MK, et al. The PRaCTICaL study of nurse led, intensive care follow-up programmes for improving long term outcomes from critical illness: a pragmatic randomised controlled trial BMJ, 2009.PMID 19837741
- [6]Gantner D, Farley K, Bailey M, et al. Mortality related to after-hours discharge from intensive care in Australia and New Zealand, 2005-2012 Intensive Care Med, 2014.PMID 25118868
- [7]Tobin AE, Santamaria JD. After-hours discharges from intensive care are associated with increased mortality Med J Aust, 2006.PMID 16584367
- [8]Schweickert WD, Pohlman MC, Pohlman AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial Lancet, 2009.PMID 19446324
- [9]Girard TD, Thompson JL, Pandharipande PP, et al. Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study Lancet Respir Med, 2018.PMID 29508705
- [10]Pun BT, Balas MC, Barnes-Daly MA, et al. Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults Crit Care Med, 2019.PMID 30339549
- [11]Barnes-Daly MA, Phillips G, Ely EW, et al. Improving Hospital Survival and Reducing Brain Dysfunction at Seven California Community Hospitals: Implementing PAD Guidelines Via the ABCDEF Bundle in 6,064 Patients Crit Care Med, 2017.PMID 27861180
- [12]Devlin JW, Skrobik Y, Gélinas C, et al. Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU Crit Care Med, 2018.PMID 30113379
- [13]Mikkelsen ME, Still M, Anderson BJ, et al. Society of Critical Care Medicine's International Consensus Conference on Prediction and Identification of Long-Term Impairments After Critical Illness Crit Care Med, 2020.PMID 32947467
- [14]Stollings JL, Devlin JW, Pun BT, et al. Implementing the ABCDEF Bundle: Top 8 Questions Asked During the ICU Liberation ABCDEF Bundle Improvement Collaborative Crit Care Nurse, 2019.PMID 30710035
- [15]Dinglas VD, Chessare CM, Davis WE, et al. Perspectives of survivors, families and researchers on key outcomes for research in acute respiratory failure Thorax, 2018.PMID 28756400
- [16]Goldfrad C, Rowan K Consequences of discharges from intensive care at night. Lancet, 2000.PMID 10791376
- [17]Rosenberg AL, Hofer TP, Hayward RA, et al. Who bounces back? Physiologic and other predictors of intensive care unit readmission Crit Care Med, 2001.PMID 11373413
- [18]Gajic O, Malinchoc M, Comfere TB, et al. The Stability and Workload Index for Transfer score predicts unplanned intensive care unit patient readmission: initial development and validation Crit Care Med, 2008.PMID 18431260
- [19]Nates JL, Nunnally M, Kleinpell R, et al. ICU Admission, Discharge, and Triage Guidelines: A Framework to Enhance Clinical Operations, Development of Institutional Policies, and Further Research Crit Care Med, 2016.PMID 27428118
- [20]De Meester K, Verspuy M, Monsieurs KG, Van Bogaert P SBAR improves nurse-physician communication and reduces unexpected death: a pre and post intervention study Resuscitation, 2013.PMID 23537699
- [21]Müller M, Jürgens J, Redaèlli M, et al. Impact of the communication and patient hand-off tool SBAR on patient safety: a systematic review BMJ Open, 2018.PMID 30139905
- [22]Burgess A, van Diggele C, Roberts C, Mellis C Teaching clinical handover with ISBAR BMC Med Educ, 2020.PMID 33272274
- [23]Hurt RT, Frazier TH, McClave SA, et al. Stress prophylaxis in intensive care unit patients and the role of enteral nutrition JPEN J Parenter Enteral Nutr, 2012.PMID 22412182
- [24]Farrell CP, Mercogliano G, Kuntz CL Overuse of stress ulcer prophylaxis in the critical care setting and beyond J Crit Care, 2010.PMID 19683892