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ICU TopicsCardiovascular

ICU · Cardiovascular

Acute aortic dissection: type A vs type B, malperfusion, and endovascular management

Also known as Aortic dissection · Type A dissection · Type B dissection · Stanford classification · TEVAR · Malperfusion syndrome

Acute aortic dissection = tear in aortic intima - blood enters media - false lumen - propagation. CLASSIFICATION (Stanford): TYPE A (ascending aorta — 65%) — SURGICAL EMERGENCY (mortality 1-2%/h untreated, 50% in 48h). TYPE B (descending aorta — distal to left subclavian — 35%) — MEDICAL management (beta-blockers, BP control); surgery/endovascular if COMPLICATED (rupture, malperfusion, refractory pain/HTN, rapid expansion). PRESENTATION: sudden TEARING chest/back pain (migrating — tracks dissection propagation), pulse deficits (asymmetric — vessel occlusion), blood pressure differential (20 mmHg between arms), new aortic regurgitation murmur, neurological deficit (stroke, paraplegia — spinal/visceral ischaemia), syncope. RISK FACTORS: hypertension (most important), connective tissue disease (Marfan, Ehlers-Danlos, Loeys-Dietz), bicuspid aortic valve, pregnancy, cocaine, trauma. DIAGNOSIS: CT aortogram (gold standard — intimal flap, true/false lumen, extent, malperfusion). MANAGEMENT: TYPE A — emergency SURGICAL repair (ascending aorta replacement ± AVR ± arch). TYPE B (uncomplicated) — medical (beta-blocker + BP control). TYPE B (complicated) — THORACIC ENDOVASCULAR AORTIC REPAIR (TEVAR) preferred over open surgery. MORTALITY: type A (untreated) 50% in 48h; type B (uncomplicated) 10% in 30 days.

high13 referencesUpdated 26 July 202612 min readVerification in progress

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Red flags

  • TYPE A dissection (ascending) — SURGICAL EMERGENCY (1-2%/h untreated mortality)
  • TYPE B (uncomplicated) — MEDICAL management; COMPLICATED — TEVAR
  • Sudden tearing chest/back pain + pulse deficit/BP differential = dissection until proven otherwise
  • Malperfusion syndrome (mesenteric, renal, limb, spinal) — emergency
  • Beta-blocker FIRST (reduce shear) then vasodilator (avoid reflex tachycardia)
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Practise this topic8 MCQs with explanations

Target exams

CICMFFICMEDIC

Red flags

  • TYPE A dissection (ascending) — SURGICAL EMERGENCY (1-2%/h untreated mortality)
  • TYPE B (uncomplicated) — MEDICAL management; COMPLICATED — TEVAR
  • Sudden tearing chest/back pain + pulse deficit/BP differential = dissection until proven otherwise
  • Malperfusion syndrome (mesenteric, renal, limb, spinal) — emergency
  • Beta-blocker FIRST (reduce shear) then vasodilator (avoid reflex tachycardia)
The one-line answer

Aortic dissection is a tear in the intima that admits blood into the media, creating a false lumen that propagates along the aorta. The Stanford system decides management: Type A (ascending aorta — 65 per cent) is a surgical emergency (1 to 2 per cent per hour untreated mortality, 50 per cent dead in 48 hours); Type B (descending, distal to the left subclavian — 35 per cent) is managed medically if uncomplicated — beta-blocker first (esmolol or labetalol, heart rate under 60), then a vasodilator (SBP 100 to 120) — and with TEVAR if complicated (rupture, malperfusion, refractory pain or hypertension). Never a vasodilator without a beta-blocker first — the reflex tachycardia increases shear and extends the flap.[1]

Meet the patient

A 58-year-old hypertensive man is brought in with sudden tearing central chest pain radiating through to his back, followed by a brief syncope. On arrival his blood pressure is 76/48, heart rate 132, JVP distended to the angle of the jaw, heart sounds muffled. Bedside echo shows a large pericardial effusion with diastolic collapse of the right ventricle, and a mobile intimal flap in the ascending aorta. The CT aortogram confirms a Stanford Type A dissection with haemopericardium.[5]

Two facts decide his next 30 minutes. This is a surgical emergency — the definitive treatment is emergency cardiothoracic surgery, which addresses both the dissection and the tamponade. And the tamponade is the one complication you operate on, not tap — because the pericardial blood was containing the retrograde rupture, and decompression can precipitate exsanguination.[5]

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References13ShowHide
  1. [1]Erbel R, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). European heart journal, 2014.PMID 25173340
  2. [2]Hiratzka LF, et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation, 2010.PMID 20233780
  3. [3]Nienaber CA, et al. Endovascular repair of type B aortic dissection: long-term results of the randomized investigation of stent grafts in aortic dissection trial. Circulation. Cardiovascular interventions, 2013.PMID 23922146
  4. [4]Brunkwall J, et al. Endovascular repair of acute uncomplicated aortic type B dissection promotes aortic remodelling: 1 year results of the ADSORB trial. European heart journal, 2014.PMID 24962744
  5. [5]Evangelista A, et al. Aortic dissection. Nature reviews. Disease primers, 2016.PMID 27440162
  6. [6]Golledge J, Eagle KA Acute aortic dissection. Lancet (London, England), 2008.PMID 18603160
  7. [7]Elliott WJ Clinical features in the management of selected hypertensive emergencies. Progress in cardiovascular diseases, 2006.PMID 16627047
  8. [8]Krenz JR, et al. Evaluation of esmolol for heart rate control in patients with acute aortic dissection. The American journal of emergency medicine, 2021.PMID 32354528
  9. [9]Ulici A, et al. Clevidipine versus sodium nitroprusside in acute aortic dissection: A retrospective chart review. The American journal of emergency medicine, 2017.PMID 28669696
  10. [10]Liu G, et al. Efficacy and Safety of preoperative Controlling Heart Rate in Patients with Acute Type A Aortic Dissection (ESCORT): protocol for a randomised controlled trial. BMJ open, 2026.PMID 41962972
  11. [11]Chen N, et al. Emergency Department Blood Pressure Management in Type B Aortic Dissection: An Analysis with Machine Learning. The western journal of emergency medicine, 2025.PMID 40561988
  12. [12]Harris KM, et al. Early Mortality in Type A Acute Aortic Dissection: Insights From the International Registry of Acute Aortic Dissection. JAMA cardiology, 2022.PMID 36001309
  13. [13]Cruz I, et al. Controlled pericardiocentesis in patients with cardiac tamponade complicating aortic dissection: experience of a centre without cardiothoracic surgery. European heart journal. Acute cardiovascular care, 2015.PMID 25182464

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