ICU SAQs · GI & nutrition
The gut mucosal barrier and the enteral nutrition
A CICM First-Part SAQ on the gut barrier — the mucus, epithelium, and GALT as the teaching framework, with packed trial numbers for early EN (ESICM infectious-complication reduction; NUTRIREA-2 route equivalence in shock) rather than unsourced translocation-mortality claims.
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Prompt
Explain the gut mucosal barrier function, how the critical illness and the fasting disrupt it, and how the early enteral nutrition maintains it.
Question
Explain the gut mucosal barrier function, how the critical illness and the fasting disrupt it, and how the early enteral nutrition maintains it.[1]
References3ShowHide
- [1]Reintam Blaser A, Starkopf J, Alhazzani W, et al. Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines. Intensive Care Medicine, 2017.PMID 28168570
- [2]Reignier J, Boisramé-Helms J, Brisard L, et al. Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2). Lancet, 2018.PMID 29128300
- [3]Puthucheary ZA, Rawal J, McPhail M, et al. Acute skeletal muscle wasting in critical illness. JAMA, 2013.PMID 24108501