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GP Topicsrespiratory-health

GP · respiratory-health

Community-acquired pneumonia

Also known as CAP · Pneumonia assessment · Lower respiratory tract infection

GP-fellowship guide to community-acquired pneumonia: aetiology from the CDC surveillance study (rhinovirus commonest, S. pneumoniae leading bacterial pathogen), CURB-65 severity scoring, corticosteroid evidence for hospitalised CAP (RR 0.67 for mortality), Cochrane null result on short-course antibiotics in outpatients, and when to refer versus manage at home.

high4 referencesUpdated 22 Aug 20263 min readVerification in progress

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Target exams

RACGP AKTRACGP KFPRACGP CCE

Red flags

  • CURB-65 score of 3 or more requires hospital admission — do not manage high-severity CAP in the community
  • Confusion, urea above 7 mmol/L, respiratory rate 30 or more, or systolic BP below 90 mmHg each independently predict mortality and mandate urgent assessment
  • Failure to improve after 48 hours of appropriate antibiotics demands CXR repeat, consideration of empyema/abscess, and specialist referral
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  • Short-answer question1
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Target exams

RACGP AKTRACGP KFPRACGP CCE

Red flags

  • CURB-65 score of 3 or more requires hospital admission — do not manage high-severity CAP in the community
  • Confusion, urea above 7 mmol/L, respiratory rate 30 or more, or systolic BP below 90 mmHg each independently predict mortality and mandate urgent assessment
  • Failure to improve after 48 hours of appropriate antibiotics demands CXR repeat, consideration of empyema/abscess, and specialist referral
Key points
  • A pathogen was detected in only 38% of hospitalised CAP cases; viruses (23%) were more commonly identified than bacteria (11%).[2]
  • CURB-65 scores severity using Confusion, Urea above 7 mmol/L, Respiratory rate 30 or more, BP below 90/60, and age 65 or older — each element predicts 30-day mortality.[1]
  • Adjunctive corticosteroids reduced all-cause mortality at 30 days in hospitalised CAP by one-third (RR 0.67) without increasing adverse events.[4]
  • No RCTs have compared short- versus longer-course antibiotics for adult outpatients with CAP — the evidence gap remains.[3]

Overview

Community-acquired pneumonia (CAP) is a leading infectious cause of hospitalisation and death among adults. In the CDC population-based surveillance study, a pathogen was detected in only 38% of cases — viruses were more commonly identified than bacteria.[2] This matters because it means empiric antibiotic choice is guided by severity and local resistance patterns, not by microbiological confirmation in most cases.

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References4ShowHide
  1. [1]Jones BE, Jones J, Bewick T, Lim WS, Aronsky D, et al. CURB-65 pneumonia severity assessment adapted for electronic decision support. Chest, 2011.PMID 21163875
  2. [2]Jain S, Self WH, Wunderink RG, Fakhran S, Balk R, et al. Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults. N Engl J Med, 2015.PMID 26172429
  3. [3]López-Alcalde J, Rodriguez-Barrientos R, Redondo-Sánchez J, Muñoz-Gutiérrez J, Molero García JM, et al. Short-course versus long-course therapy of the same antibiotic for community-acquired pneumonia in adolescent and adult outpatients. Cochrane Database Syst Rev, 2018.PMID 30188565
  4. [4]Bergmann F, Pracher L, Sawodny R, Blaschke A, Gelbenegger G, et al. Efficacy and Safety of Corticosteroid Therapy for Community-Acquired Pneumonia: A Meta-Analysis and Meta-Regression of Randomized, Controlled Trials. Clin Infect Dis, 2023.PMID 37876267

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