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GP Topicsmusculoskeletal-presentations

GP · musculoskeletal-presentations

Low back pain

Also known as Lumbago · Nonspecific low back pain · Mechanical back pain · Lumbar radiculopathy · Sciatica

GP-fellowship guide to low back pain: diagnostic triage into nonspecific pain, radicular syndrome and specific pathology, the red flags that mandate urgent imaging (cauda equina, fracture, cancer, infection), why routine imaging and passive treatment harm, the drug evidence stripped of habit (PACE, Machado, Goldberg, OPAL, SPACE), exercise and cognitive functional therapy for persistence, and when radiculopathy leaves primary care.

high48 referencesUpdated 21 Aug 202614 min readVerification in progress

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RACGP AKTRACGP KFPRACGP CCE

Red flags

  • New saddle anaesthesia, urinary retention or overflow incontinence, or bilateral neurological signs means suspected cauda equina syndrome — an emergency needing immediate imaging and neurosurgical referral, not review in a week
  • Age over 50 with minor trauma, any age with significant trauma, chronic corticosteroid use or known osteoporosis raises vertebral fracture probability — image before you reassure
  • A history of any cancer with new back pain assumes metastasis until excluded
  • Fever, intravenous drug use or immunosuppression with new back pain suggests spinal infection — back pain (79%) and fever (72%) are its most common symptoms
  • Progressive motor weakness or new reflex asymmetry is a time-critical neurological deficit — escalate same day
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Target exams

RACGP AKTRACGP KFPRACGP CCE

Red flags

  • New saddle anaesthesia, urinary retention or overflow incontinence, or bilateral neurological signs means suspected cauda equina syndrome — an emergency needing immediate imaging and neurosurgical referral, not review in a week
  • Age over 50 with minor trauma, any age with significant trauma, chronic corticosteroid use or known osteoporosis raises vertebral fracture probability — image before you reassure
  • A history of any cancer with new back pain assumes metastasis until excluded
  • Fever, intravenous drug use or immunosuppression with new back pain suggests spinal infection — back pain (79%) and fever (72%) are its most common symptoms
  • Progressive motor weakness or new reflex asymmetry is a time-critical neurological deficit — escalate same day
Key points
  • Low back pain is a symptom, not a diagnosis. Diagnostic triage allocates every presentation to nonspecific low back pain (90–95% of cases), radicular syndrome (about 5–10%), or specific spinal pathology (below 1%).[23]
  • Most acute episodes improve substantially within 4–6 weeks, but recurrence is the rule. First-line care is advice to stay active, superficial heat, and NSAIDs; bed rest, paracetamol, oral corticosteroids and opioids are not supported.[25][22]
  • Routine imaging does not improve outcomes and drives cascades of incidental findings and interventions. Reserve imaging for red flags: cauda equina features, fracture risk, cancer history, or infection signs.[8]
  • New saddle anaesthesia, urinary retention or overflow incontinence, or bilateral neurological signs means suspected cauda equina syndrome: emergency MRI and neurosurgical referral the same day.[29][48]

Overview

Low back pain is pain between the 12th ribs and the gluteal folds. It is the leading cause of disability worldwide: in 2020 it affected 619 million people globally, and prevalence is projected to reach 843 million cases by 2050. Lifetime prevalence reaches 84%, and about 23% of adults live with chronic low back pain.[37][11][25]

Nearly all presentations cannot be attributed to a specific nociceptive cause. Only a small proportion have a well-understood pathological cause such as vertebral fracture, malignancy or infection. This single fact organises general-practice management: the task is not to find the lesion, but to exclude the dangerous causes, identify modifiable risk of chronicity, and keep the patient active and working.[25]

Practice lags far behind this evidence. Globally, clinicians underuse recommended first-line treatments and overuse imaging, rest, opioids, spinal injections and surgery; Australian commentary describes the same pattern — overuse of less effective, expensive options while effective inexpensive options are underused.[26][41]

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References48ShowHide
  1. [1]Devillé WL et al. The test of Lasègue: systematic review of the accuracy in diagnosing herniated discs. Spine (Phila Pa 1976), 2000.PMID 10788860
  2. [2]Jarvik JG et al. Rapid magnetic resonance imaging vs radiographs for patients with low back pain: a randomized controlled trial. JAMA, 2003.PMID 12783911
  3. [3]French SD et al. Superficial heat or cold for low back pain. Cochrane Database Syst Rev, 2006.PMID 16437495
  4. [4]Weinstein JN et al. Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial. JAMA, 2006.PMID 17119140
  5. [5]Peul WC et al. Surgery versus prolonged conservative treatment for sciatica. N Engl J Med, 2007.PMID 17538084
  6. [6]Hill JC et al. A primary care back pain screening tool: identifying patient subgroups for initial treatment. Arthritis Rheum, 2008.PMID 18438893
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  9. [9]Dahm KT et al. Advice to rest in bed versus advice to stay active for acute low-back pain and sciatica. Cochrane Database Syst Rev, 2010.PMID 20556780
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  13. [13]Abdel Shaheed C et al. Interventions available over the counter and advice for acute low back pain: systematic review and meta-analysis. J Pain, 2014.PMID 24373568
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  19. [19]Fernandez M et al. Advice to Stay Active or Structured Exercise in the Management of Sciatica: A Systematic Review and Meta-analysis. Spine (Phila Pa 1976), 2015.PMID 26165218
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  21. [21]Machado GC et al. Non-steroidal anti-inflammatory drugs for spinal pain: a systematic review and meta-analysis. Ann Rheum Dis, 2017.PMID 28153830
  22. [22]Qaseem A et al. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med, 2017.PMID 28192789
  23. [23]Bardin LD et al. Diagnostic triage for low back pain: a practical approach for primary care. Med J Aust, 2017.PMID 28359011
  24. [24]Krebs EE et al. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial. JAMA, 2018.PMID 29509867
  25. [25]Hartvigsen J et al. What low back pain is and why we need to pay attention. Lancet, 2018.PMID 29573870
  26. [26]Foster NE et al. Prevention and treatment of low back pain: evidence, challenges, and promising directions. Lancet, 2018.PMID 29573872
  27. [27]Parreira P et al. Risk factors for low back pain and sciatica: an umbrella review. Spine J, 2018.PMID 29792997
  28. [28]Will JS et al. Mechanical Low Back Pain. Am Fam Physician, 2018.PMID 30252425
  29. [29]Babu JM et al. Spinal Emergencies in Primary Care Practice. Am J Med, 2019.PMID 30291829
  30. [30]Schreijenberg M et al. Paracetamol is ineffective for acute low back pain even for patients who comply with treatment: complier average causal effect analysis of a randomized controlled trial. Pain, 2019.PMID 31453982
  31. [31]Buell KG et al. Expediting the management of cauda equina syndrome in the emergency department through clinical pathway design. BMJ Open Qual, 2019.PMID 31799444
  32. [32]Oliveira CB et al. Epidural corticosteroid injections for lumbosacral radicular pain. Cochrane Database Syst Rev, 2020.PMID 32271952
  33. [33]Magrey MN et al. Recognizing Axial Spondyloarthritis: A Guide for Primary Care. Mayo Clin Proc, 2020.PMID 32736944
  34. [34]Cashin AG et al. Efficacy, acceptability, and safety of muscle relaxants for adults with non-specific low back pain: systematic review and meta-analysis. BMJ, 2021.PMID 34233900
  35. [35]Hayden JA et al. Exercise therapy for chronic low back pain. Cochrane Database Syst Rev, 2021.PMID 34580864
  36. [36]Kent P et al. Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial. Lancet, 2023.PMID 37146623
  37. [37]GBD 2021 Low Back Pain Collaborators Global, regional, and national burden of low back pain, 1990-2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol, 2023.PMID 37273833
  38. [38]Jones CMP et al. Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial. Lancet, 2023.PMID 37392748
  39. [39]Verville L et al. Systematic Review to Inform a World Health Organization (WHO) Clinical Practice Guideline: Benefits and Harms of Structured Exercise Programs for Chronic Primary Low Back Pain in Adults. J Occup Rehabil, 2023.PMID 37991647
  40. [40]Al Taha K et al. Multidisciplinary and Coordinated Management of Osteoporotic Vertebral Compression Fractures: Current State of the Art. J Clin Med, 2024.PMID 38398244
  41. [41]Pirotta M et al. Best practice care for acute low back pain: A new clinical standard to assist general practitioners. Aust J Gen Pract, 2024.PMID 39226604
  42. [42]Hancock M et al. Patients with worse disability respond best to cognitive functional therapy for chronic low back pain: a pre-planned secondary analysis of a randomised trial. J Physiother, 2024.PMID 39327170
  43. [43]Cashin AG et al. Analgesic effects of non-surgical and non-interventional treatments for low back pain: a systematic review and meta-analysis of placebo-controlled randomised trials. BMJ Evid Based Med, 2025.PMID 40101974
  44. [44]Hancock M et al. Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): 3-year follow-up of a randomised, controlled trial. Lancet Rheumatol, 2025.PMID 40780241
  45. [45]Conti J et al. Infectious spondylodiscitis: Epidemiology, diagnosis, microbiological findings, clinical features and outcomes in a 14-year retrospective study. Eur J Clin Microbiol Infect Dis, 2025.PMID 41023355
  46. [46]Thiveos L et al. Does Cognitive Functional Therapy Reduce the Amount of Opioids Dispensed for Chronic Low Back Pain Over 12 Months: A Secondary Analysis From the RESTORE Trial. Eur J Pain, 2026.PMID 41979226
  47. [47]Najjar E et al. Reassessing the clock in cauda equina syndrome: a systematic review and meta-analysis of surgical timing and outcomes. Spine J, 2026.PMID 41991105
  48. [48]Conte A et al. Cauda Equina Syndrome-A 2025 Narrative Review. Br J Hosp Med (Lond), 2026.PMID 42053010

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