EM · Postpartum haemorrhage
Postpartum haemorrhage
Also known as PPH · Primary postpartum haemorrhage · Obstetric haemorrhage
The postpartum haemorrhage — the primary PPH (the blood loss over 500 mL within the 24 hours of the delivery, or the over 1000 mL after the Caesarean) and the secondary PPH (the bleeding from the 24 hours to the 12 weeks postpartum). The four Ts of the cause (the Tone — the uterine atony, the commonest at 70 per cent; the Trauma — the vaginal or the cervical tear; the Tissue — the retained products; the Thrombin — the coagulopathy). The management: the ABCDE, the two large-bore cannulae, the crossmatch 4 units, the fluid resuscitation, the uterotonics (the oxytocin 10 IU IM or 5 IU IV, the ergometrine 500 mcg IM — avoid in the hypertension; the carboprost 250 mcg IM every 15 minutes up to 8 doses — avoid in the asthma; the misoprostol 800 mcg per rectum), the tranexamic acid 1 g IV, the Bakri balloon, the bimanual compression, the surgical ligation, the hysterectomy for the refractory. ACEM-primary, globally tagged.
Checked against its sources on 3 Sept 2026
On this page
Study tools
Your progress
Saved on this device.
Target exams
Red flags
- The estimated blood loss is systematically underestimated — manage on the physiological derangement (the tachycardia, the hypotension, the raised lactate), not the drip count
- The uterine atony is the commonest cause at 70 per cent — the first move is the uterine massage and the oxytocin while the ABCDE proceeds
- The ergometrine is contraindicated in the hypertension and the pre-eclampsia (the vasopressor, the hypertensive crisis); the carboprost is contraindicated in the asthma (the bronchospasm)
- The tranexamic acid 1 g IV within the 3 hours — the earlier the better, the effect falls by the hour after the onset
- The secondary PPH from the 24 hours to the 12 weeks — the retained products and the infection are the commonest cause; do NOT forget the chlamydia and the gonorrhoea
Meet the patient
A 32-year-old multigravida, oxytocin-augmented through an 18-hour labour, delivers a 4.2 kg infant. The placenta looks complete. Thirty minutes later she is pale and restless — HR 124, BP 92/58 — and the sheet is soaked. The uterus is soft and boggy at the umbilicus, pouring bright-red lochia and clots.[1]
Two questions decide her next hour, and they decide every PPH: why is she bleeding? (the four Ts) and can I stop it before she loses another litre? (resuscitate and source-control in parallel). Hold those two and the rest of the topic slots into place.[3]
References5ShowHide
- [1]WOMAN Trial Collaborators Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet, 2017.PMID 28456509
- [2]Gayet-Ageron A, Prieto-Merino D, Ker K, et al. Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Lancet, 2018.PMID 29126600
- [3]Zúñiga Gómez E, Durán Monge PR, Castro Rivero LC Contemporary Approach to Postpartum Hemorrhage: Early Diagnosis and Evidence-Based Therapeutic Management. Cureus, 2026.PMID 42147550
- [4]Gallos I, Devall A, Martin J, et al. Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage. N Engl J Med, 2023.PMID 37158447
- [5]Widmer M, Piaggio G, Nguyen TMH, et al. Heat-Stable Carbetocin versus Oxytocin to Prevent Hemorrhage after Vaginal Birth. N Engl J Med, 2018.PMID 29949473