EM SAQs · Respiratory failure (type 1 and 2)
Respiratory failure — type 2
An ACEM-style SAQ on the type 2 respiratory failure.
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Prompt
A 70-year-old man with severe COPD presents with worsening breathlessness. His oxygen saturation is 84 per cent on room air. After controlled oxygen, his arterial blood gas shows pH 7.27, PaCO2 9.5 kPa, PaO2 7.5 kPa, and bicarbonate 28 mmol/L. Discuss the classification and management. (10 marks)
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Classification: The type 2 (hypercapnic) respiratory failure, acutely decompensated — the PaCO2 raised (9.5 kPa), the pH low (7.27), and the bicarbonate only mildly raised (28, not the fully-compensated chronic) — the acute-on-chronic decompensation of the COPD.[3]
Management:
- The ABCDE, the controlled oxygen targeting the 88 to 92 per cent (the AVOIDANCE of the high-flow oxygen and the CO2 narcosis — the Haldane effect, the reduced hypoxic drive, the V/Q mismatch).
- The nebulised bronchodilators — the salbutamol and the ipratropium (the air or the controlled oxygen driven).
- The systemic corticosteroids — the prednisolone 30 to 40 milligrams.
- The antibiotics if the infective trigger (the Anthonisen criteria).
- The non-invasive ventilation (the BiPAP) — the first-line for the decompensated acidosis (the pH 7.27). The continuous, the monitoring of the arterial blood gas for the improvement (the rising pH and the falling carbon dioxide).[4]
- The intubation if the NIV fails, the contraindicated, or the unconscious.
- The investigation and the treatment of the trigger.
Disposition: The high-dependency or the intensive care, the continuous monitoring, the gradual wean of the NIV.[4]
References2ShowHide
- [3]MacIntyre NR Acute hypercapnic respiratory failure in chronic obstructive pulmonary disease. Respiratory Care, 2023.PMID 37353327
- [4]Plant PK, Owen JL, Elliott MW. Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial Lancet, 2000.PMID 10859037