EM SAQs · Heat illness and heat stroke
Exertional heat stroke in the collapsed soldier
An ACEM-style SAQ on the recognition and rapid cooling of exertional heat stroke, the cooling-technique rationale, the drug roles, and the end-organ complications.
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(a) Recognition and cooling (8 marks). This is exertional heatstroke: a core temperature above 40 °C with central nervous system dysfunction during strenuous exercise; no specific therapy other than rapid cooling is available.[14] Cool immediately by cold-water or ice-water immersion, the method proven to have the fastest cooling rates; in 274 race patients it cooled at 0.22 °C per minute with 100 per cent survival.[17][16] Aim to reduce core temperature below 39 °C within 30 minutes.[13]
(b) Justification and drugs (5 marks). Water immersion in cold, colder or ice water cooled faster than passive cooling, with no single water temperature range faster than another.[5] Antipyretics, dantrolene and NSAIDs are not recommended for a heat casualty; in a randomised trial, dantrolene 2 mg/kg intravenously did not shorten cooling time.[13][7] The circulatory failure is mostly distributive with relative or absolute hypovolaemia.[9]
(c) Complications and prognosis (3 marks). Exertional heatstroke pathophysiology includes systemic inflammatory response syndrome and coagulopathy with disseminated intravascular coagulation, and in catastrophic cases with severe liver damage endotoxin leaks into the circulation.[18] Patients generally require hospitalisation to monitor for complications despite rapid cooling, and those adequately cooled within 30 minutes have excellent outcomes.[15]
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- [4]Eifling KP, Gaudio FG, Dumke C, et al. Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Heat Illness: 2024 update. Wilderness & Environmental Medicine, 2024.PMID 38425235
- [5]Douma MJ, Aves T, Allan KS, et al. First aid cooling techniques for heat stroke and exertional hyperthermia: A systematic review and meta-analysis. Resuscitation, 2020.PMID 31981710
- [7]Bouchama A, Cafege A, Devol EB, et al. Ineffectiveness of dantrolene sodium in the treatment of heatstroke. Crit Care Med, 1991.PMID 1989755
- [9]Bouchama A, Dehbi M, Chaves-Carballo E Cooling and hemodynamic management in heatstroke: practical recommendations. Crit Care, 2007.PMID 17498312
- [10]Casa DJ, DeMartini JK, Bergeron MF, et al. National Athletic Trainers' Association Position Statement: Exertional Heat Illnesses. J Athl Train, 2015.PMID 26381473
- [13]DeGroot DW, Ruby B, Koo A, O'Connor FG Far from Home: Heat-Illness Prevention and Treatment in Austere Environments. Wilderness Environ Med, 2025.PMID 40262113
- [14]Bouchama A, Abuyassin B, Lehe C, et al. Classic and exertional heatstroke. Nature reviews. Disease primers, 2022.PMID 35115565
- [15]Gauer R, Meyers BK Heat-Related Illnesses. American family physician, 2019.PMID 30990296
- [16]Demartini JK, Casa DJ, Stearns R, et al. Effectiveness of cold water immersion in the treatment of exertional heat stroke at the Falmouth Road Race. Medicine and science in sports and exercise, 2015.PMID 24983342
- [17]McDermott BP, Casa DJ, Ganio MS, et al. Acute whole-body cooling for exercise-induced hyperthermia: a systematic review. Journal of athletic training, 2009.PMID 19180223
- [18]Garcia CK, Renteria LI, Leite-Santos G, et al. Exertional heat stroke: pathophysiology and risk factors. BMJ medicine, 2022.PMID 36936589