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Anaes VivasApplied cardiovascular & respiratory physiology

Anaes Vivas · Applied cardiovascular & respiratory physiology

Data viva — the ventilatory control loop

A Primary data viva — trace the ventilatory control loop; identify CO2 via central chemoreceptors as the dominant drive; explain the opioid/anaesthetic depression of the CO2-response curve and hypoxic response.

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Target exams

ANZCAFRCAABAEDAIC
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Target exams

ANZCAFRCAABAEDAIC
Prompt
A feedback loop diagram shows sensors (central and peripheral chemoreceptors), a medullary controller, and respiratory muscle effectors, with arterial gases feeding back. Explain the loop, identify the dominant drive, and state the effect of opioids on the CO2 response.

Stimulus

A feedback loop diagram shows sensors (central and peripheral chemoreceptors), a medullary controller, and respiratory muscle effectors, with arterial gases feeding back. Explain the loop, identify the dominant drive, and state the effect of opioids on the CO2 response.[2]

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References2ShowHide
  1. [1]MacDonald TJA, et al. Going with the respiratory flow: The carotid body mediates human ventilatory acclimatization during high-altitude sojourn. J Physiol, 2026.PMID 42210543
  2. [2]Guyenet PG Regulation of breathing and autonomic outflows by chemoreceptors. Compr Physiol, 2014.PMID 25428853
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