Anaes Vivas · Applied cardiovascular & respiratory physiology
Data viva — adverse-drug-reaction classification and antidotes
A Primary data viva — read a Type A/B ADR diagram and an antidote table; classify warfarin bleeding, paracetamol hepatotoxicity, anaphylaxis and LAST; give their antidotes (dose reduction / N-acetylcysteine / adrenaline / lipid emulsion).
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A diagram shows the Type A (Augmented, dose-dependent, predictable) versus Type B (Bizarre, dose-independent, unpredictable) classification of adverse drug reactions, with example drugs and a bell-curve versus scattered-cluster illustration. A side table lists specific antidotes: paracetamol — N-acetylcysteine; bupivacaine LAST — lipid emulsion; opioid — naloxone; benzodiazepine — flumazenil; malignant hyperthermia — dantrolene. Interpret the diagram, classify four named reactions, and state the antidote or rescue for each.
References3ShowHide
- [2]Guo C, et al. Acetaminophen-induced liver injury redox mechanism. Metabolites, 2026.PMID 42346403
- [3]Pham DT, et al. New long-acting local anesthetics: recent formulations and safety. Curr Opin Anaesthesiol, 2026.PMID 42228505
- [4]Michel MP, et al. Guidelines: Diagnosis and management of perioperative immediate hypersensitivity reactions 2025. Anaesth Crit Care Pain Med, 2026.PMID 42335666