Anaes Vivas · TIVA & target-controlled infusion
TIVA and TCI — equipment and data viva
An equipment/data viva on the TCI pump: the compartment model, the Schnider model and effect-site targeting, the prediction-versus-measurement principle, and the use of a processed-EEG depth monitor to confirm anaesthetic depth.
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Prompt
You are shown a TCI syringe pump with the Schnider propofol model selected, the patient's age, height and weight entered, and a target effect-site concentration of four micrograms per millilitre displayed. Discuss how the pump works, the model it uses, and how you would confirm the anaesthetic is adequate.
Stimulus
You are shown a TCI syringe pump with the Schnider propofol model selected, the patient's age, height and weight entered, and a target effect-site concentration displayed. Discuss how the pump works, the model it uses, and how you would confirm the anaesthetic is adequate[5][2].
References5ShowHide
- [1]Ye J, et al. A Prospective Study of Marsh PK-PD Model and Schnider PK-PD Model During Anesthesia Induction for Obese Patients Undergoing Elective Heart Surgery. Pharmacol Res Perspect, 2026.PMID 42286797
- [2]Introna M, et al. Target concentrations of propofol predicted by four different pharmacokinetic/pharmacodynamic models to induce loss of consciousness in neurosurgical patients. J Anesth Analg Crit Care, 2026.PMID 42231496
- [3]Bartošová T, Šíma M, Prskavec T, et al. Deep hypothermia reduces the predictive accuracy of the Eleveld propofol model: Population pharmacokinetic modelling in cardiac surgery. Biomed Pharmacother, 2026.PMID 42140058
- [4]Ramesh S, et al. Integrated Advanced Monitoring and Target-Controlled Infusion Anesthesia in a Child With Arthrogryposis Multiplex Congenita. Cureus, 2026.PMID 42359210
- [5]Sahinovic MM, et al. Clinical Pharmacokinetics and Pharmacodynamics of Propofol. Clin Pharmacokinet, 2018.PMID 30019172