Anaes Vivas · Physiology, physics and equipment
Procedural sedation outside the OR — Viva
Viva on sedation agents, monitoring, capnography, and recovery/discharge criteria.
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Prompt
An 8-year-old needs sedation for an urgent fracture reduction in the ED.
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Viva Stems
- What is the sedation continuum and why is it clinically important? Cover anxiolysis through general anaesthesia and the risk of inadvertent deep sedation with reactive top-ups.[2][9]
- Compare propofol, ketamine and dexmedetomidine for this child, noting that children carry higher sedation risk and that propofol MAC sedation is not label-recommended in children.[3][4][7][9][12]
- What is the evidence for capnography in procedural sedation? A 13-trial meta-analysis found less desaturation and assisted ventilation; ANZCA recommends continuous waveform capnography where verbal contact is lost.[10][9]
- What are the discharge criteria after procedural sedation in the ED? Supervised recovery, practitioner-authorised discharge, responsible-adult escort, written instructions.[9]
- How do you manage apnoea after the last propofol bolus? Propofol has no reversal — open the airway, support ventilation, with monitoring and resuscitation equipment already at hand.[3][9]
References8ShowHide
- [2]Benzoni T, Agarwal A, Cascella M, et al. Procedural Sedation. StatPearls, 2025.PMID 31869149
- [3]Fresenius Kabi USA, LLC DIPRIVAN (propofol) injection, emulsion 2025.Source
- [4]Par Health USA, LLC KETALAR (ketamine hydrochloride) injection 2026.Source
- [7]Hospira, Inc. PRECEDEX (dexmedetomidine hydrochloride) injection 2026.Source
- [9]Australian and New Zealand College of Anaesthetists PG09(G) Guideline on procedural sedation 2023 2023.Source
- [10]Saunders R, Struys MMRF, Pollock RF, et al. Patient safety during procedural sedation using capnography monitoring: a systematic review and meta-analysis. BMJ Open, 2017.PMID 28667196
- [11]Weerink MAS, Struys MMRF, Hannivoort LN, et al. Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine. Clin Pharmacokinet, 2017.PMID 28105598
- [12]Stern J, Agarwal A, Pozun A, et al. Pediatric Procedural Sedation. StatPearls, 2025.PMID 34283466