Anaes Vivas · Applied cardiovascular & respiratory physiology
Data viva — the oxyhaemoglobin dissociation curve
A Primary data viva — read P50 and the plateau; explain why the pulse oximeter lags PaO2; predict the effect of right-shift factors (H+, CO2, temperature, 2,3-DPG) and left-shift states on loading and unloading.
On this page
Study tools
Target exams
ANZCAFRCAABAEDAIC
Prompt
The oxyhaemoglobin dissociation curve is shown with P50 marked and dashed right- and left-shifted curves. Define P50, explain the plateau, and state what shifts the curve right and left and what each shift means for tissue oxygen delivery.
Stimulus
The oxyhaemoglobin dissociation curve is shown with P50 marked and dashed right- and left-shifted curves. Define P50, explain the plateau, and state what shifts the curve right and left and what each shift means for tissue oxygen delivery.[1][2]
References3ShowHide
- [1]Dash RK, Korman B, et al. Simple accurate mathematical models of blood HbO2 and HbCO2 dissociation curves at varied physiological conditions: evaluation and comparison with other models. Eur J Appl Physiol, 2016.PMID 26298270
- [2]Demir ZA, Bingül ES, et al. Foundations and Advancements in Hemodynamic Monitoring: Part I-Elements of Hemodynamics. Turk J Anaesthesiol Reanim, 2025.PMID 40150830
- [4]Karakurt Y, Can E. Association of Day-1 Hemoglobin Oxygen Affinity (p50) with Severe Intraventricular Hemorrhage in Preterm Infants. Indian Pediatr, 2026.PMID 41949748