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Anaes VivasApplied cardiovascular & respiratory physiology

Anaes Vivas · Applied cardiovascular & respiratory physiology

Data viva — the neuromuscular junction and drug sites

A Primary data viva — read the NMJ sequence; locate the receptor, the release site and acetylcholinesterase; state where each relaxant and reversal agent acts.

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ANZCAFRCAABAEDAIC
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Target exams

ANZCAFRCAABAEDAIC
Prompt
A Primary data viva — read the NMJ sequence; locate the receptor, the release site and acetylcholinesterase; state where each relaxant and reversal agent acts.

Stimulus

A labelled neuromuscular junction diagram shows ACh vesicle release, the nicotinic receptor, acetylcholinesterase, and the sites of action of suxamethonium, rocuronium, neostigmine and sugammadex. Outline the normal sequence and the site of action of each drug.

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References3ShowHide
  1. [1]Wood SJ, Slater CR. Safety factor at the neuromuscular junction. Prog Neurobiol, 2001.PMID 11275359
  2. [5]Ishihara H, et al. Anaphylaxis After a Third Exposure to Sugammadex. Anesth Prog, 2025.PMID 41905390
  3. [2]Sato M, et al. Suspected Neostigmine-Associated Bronchospasm Complicated by Pulmonary Edema During General Anesthesia: A Case Report. Cureus, 2026.PMID 42311723
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