Anaes Vivas · Volatile & inhalational agents
Nitrous oxide pharmacology
Viva on the pharmacology of nitrous oxide and the rationale for its declining use.
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Target exams
ANZCAFRCAABAEDAICFCAIFCA_SA
Prompt
A data table comparing the MAC, blood-gas partition coefficient and key adverse effects of nitrous oxide, sevoflurane, isoflurane and desflurane.
Stimulus
A data table comparing the MAC, blood-gas partition coefficient and key adverse effects of nitrous oxide, sevoflurane, isoflurane and desflurane. The candidate is asked to interpret the row for nitrous oxide and to discuss its pharmacology and its current place in practice.
References4ShowHide
- [8]Kichili N, et al. Analyzing the Efficacy and Potential Risks of Nitrous Oxide for Pain Management During Labor: A Narrative Review Clin Pharmacol, 2026.PMID 41737234
- [6]Kayak EA, et al. A summary guide for detecting and reducing nitrous oxide infrastructure leaks in healthcare facilities Anaesth Intensive Care, 2026.PMID 42290092
- [2]Tikaria R, et al. The Toxic Legacy of Recreational Nitrous Oxide Use: A Systematic Review and Meta-Analysis of Multisystem Complications From Functional Vitamin B12 Deficiency Cureus, 2026.PMID 42306345
- [1]Li W, et al. A case report of nitrous oxide-induced subacute combined degeneration complicated with neurosyphilis in a 23-year-old female BMC Neurol, 2026.PMID 42321648