Anaes Vivas · Anaesthetic adjuncts
Morphine versus fentanyl
Viva comparing morphine and fentanyl pharmacology.
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Prompt
A comparison table of morphine and fentanyl (potency, onset, duration, histamine release, active metabolites, renal clearance).
Stimulus
A comparison table of morphine and fentanyl (potency, onset, duration, histamine release, active metabolites, renal clearance).
References7ShowHide
- [1]Hermens JM, Ebertz JM, Hanifin JM, et al. Comparison of histamine release in human skin mast cells induced by morphine, fentanyl, and oxymorphone. Anesthesiology, 1985.PMID 2578752
- [2]Klimas R, Mikus G, et al. Morphine-6-glucuronide is responsible for the analgesic effect after morphine administration. Br J Anaesth, 2014.PMID 24985077
- [3]Slater NA, Todd AM, Trimmier MC, et al. Morphine Use in Renal Failure: A Case Report of Single-Dose Morphine Toxicity in a Patient Requiring Peritoneal Dialysis. J Pharm Pract, 2020.PMID 31248317
- [4]Dahan A, Aarts L, et al. Incidence, Reversal, and Prevention of Opioid-induced Respiratory Depression. Anesthesiology, 2010.PMID 20010421
- [5]Ladha KS, Kato R, et al. A prospective study of post-cesarean delivery hypoxia after spinal anesthesia with intrathecal morphine 150 micrograms. Int J Obstet Anesth, 2017.PMID 28964640
- [7]Edinoff AN, Kaplan LA, et al. Full Opioid Agonists and Tramadol: Pharmacological and Clinical Considerations. Anesthesiol Pain Med, 2021.PMID 34692448
- [11]Palmer CM, Emerson S, Volgoropolous D, Alves D. Dose-response relationship of intrathecal morphine for postcesarean analgesia. Anesthesiology, 1999.PMID 9952150