Anaes Vivas · Malignant hyperthermia
Equipment viva — dantrolene and the MH pack
An equipment viva on dantrolene and its reconstitution — the poorly soluble powder versus the faster nanocrystalline suspension, the dose, the contents of the MH pack, and where it must be stocked.
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ANZCAFRCAABAEDAIC
Prompt
A vial of dantrolene and the contents of the theatre malignant hyperthermia pack.
Stimulus
A vial of dantrolene sodium, with its diluent, alongside the labelled malignant hyperthermia pack kept in the theatre suite. The examiner asks you to describe the drug, how you would prepare it, and the contents and location of the pack.
References3ShowHide
- [16]Krause T, Gerbershagen MU, Fiege M, Weisshorn R, Wappler F. Dantrolene — a review of its pharmacology, therapeutic use and new developments. Anaesthesia, 2004.PMID 15023108
- [17]Schuster F, Johannsen S, et al. [Pharmacological Treatment of Malignant Hyperthermia: Update 2019]. Anasthesiol Intensivmed Notfallmed Schmerzther, 2019.PMID 31525788
- [5]Larach MG, Riazi S, Rosenberg H. Dantrolene Should Be Readily Available Wherever Malignant Hyperthermia Triggering Drugs Are Stocked. Anesthesia & Analgesia, 2019.PMID 31478931