Anaes Vivas · Local anaesthetic systemic toxicity
Data viva — LAST toxicity stages chart
Data viva on toxicity stages — low (numbness, tingling); moderate (agitation, seizure); high (coma, cardiac arrest). Dose-response.
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Prompt
A chart showing plasma local anaesthetic concentration vs clinical effect. Interpret and apply.
Stimulus
A chart shows plasma local anaesthetic concentration (mcg/mL) against clinical effect. At 1 to 5 mcg/mL: numbness, circumoral tingling. At 5 to 10: visual disturbance, agitation, seizure. Above 10: coma, cardiac arrest. Interpret and apply.
[3]References2ShowHide
- [3]Uysal AI, et al. Local anesthesia: safety and limitations. Aesthet Plast Surg, 2026.PMID 41559381
- [41559382]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.