Anaes Vivas · Applied pharmacology
Intravenous induction agents — the receptor dichotomy, the recovery-by-redistribution, and the clinical selection
The IV induction agents viva — the GABA-A-versus-NMDA receptor dichotomy, the three-compartment model and the recovery-by-redistribution principle, the haemodynamic spectrum, the propofol infusion syndrome, the etomidate-adrenal axis debate, and the patient-to-agent selection algorithm. A 15-minute structured viva covering mechanism, pharmacokinetics, pharmacodynamics, the comparison of the four agents, and the critically-ill selection scenario. Anchored to the Sahinovic, Krasowski, Domino, Hughes, Albert, Kam, Bray, De Sloovere/BIKe-protocol, Goyal, Sciorilli and Andriazzi references.
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Show candidate four ampoules side by side (or a labelled image of the GABA-A and NMDA receptors). The viva opens with the broadest question — "Tell me about the intravenous induction agents" — and narrows through the mechanism, the pharmacokinetics, the comparison, and the critically-ill selection.
References14ShowHide
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- [9]Hospira Inc. PROPOFOL INJECTION, EMULSION — prescribing information. DailyMed, 2026.Source
- [10]Hospira Inc. AMIDATE (ETOMIDATE) INJECTION, SOLUTION — prescribing information. DailyMed, 2026.Source
- [11]Henry Schein Inc. KETAMINE HYDROCHLORIDE INJECTION — prescribing information. DailyMed, 2026.Source
- [12]Goyal S, Agrawal A. Ketamine in status asthmaticus: A review Indian J Crit Care Med, 2013.PMID 24082612
- [13]Sciorilli JV, et al. Is ketamine safe for traumatic brain injury? A systematic review and meta-analysis J Crit Care, 2026.PMID 41197253
- [14]Andriazzi VH, et al. Etomidate Versus Ketamine for Emergency Intubation in Critically Ill Patients: An Updated Meta-Analysis and Systematic Review J Intensive Care Med, 2026.PMID 42299661