Anaes Vivas · Applied cardiovascular & respiratory physiology
Data viva — the four hypersensitivity types
A Primary data viva — identify each hypersensitivity type by mechanism, immunoglobulin and timing; give an anaesthetic example; explain anaphylaxis as Type I IgE mast cell degranulation.
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Prompt
A Primary data viva — identify each hypersensitivity type by mechanism, immunoglobulin and timing; give an anaesthetic example; explain anaphylaxis as Type I IgE mast cell degranulation.
Stimulus
A four-box diagram shows the Gell and Coombs hypersensitivity types (I, II, III, IV) with their mechanisms and timing. Outline each type, give an example relevant to anaesthesia, and state the mechanism of perioperative anaphylaxis.
References2ShowHide
- [3]Takazawa T, et al. Perioperative anaphylaxis in Japan: Epidemiology, diagnosis, and challenges. Allergol Int, 2026.PMID 41455630
- [6]Tanei R. Revisiting Atopy: The IgE-Dependent Amplification Loop as a Forgotten Driver of Atopic Dermatitis. Pathophysiology, 2026.PMID 42347026