Anaes · Applied anatomy
Brachial plexus anatomy
Also known as Brachial plexus · Interscalene block · Supraclavicular block · Infraclavicular block · Axillary block · Erb palsy
The brachial plexus supplies the entire upper limb and is the most blocked nerve structure in regional anaesthesia. Its anatomy is taught as a five-stage sequence — roots, trunks, divisions, cords and branches — that maps directly onto the four classic approaches to plexus blockade. The framework rests on six exam-critical ideas. First, the plexus is formed by the ventral rami of C5, C6, C7, C8 and T1 (the roots), which unite into three trunks: the upper trunk (C5-C6), the middle trunk (C7) and the lower trunk (C8-T1). Second, each trunk splits into an anterior and a posterior division; the six divisions regroup into three cords named by their relationship to the axillary artery — the lateral, medial and posterior cords. Third, the cords give rise to five terminal branches: the musculocutaneous nerve (lateral cord, elbow flexors and lateral forearm), the axillary nerve (posterior cord, deltoid and teres minor), the radial nerve (posterior cord, all the extensor compartment of arm and forearm), the median nerve (lateral and medial cords, most of the thenar muscles and lateral palm) and the ulnar nerve (medial cord, the intrinsic hand muscles and medial one and a half digits). Fourth, the plexus runs a recognisable course — between the scalenus anterior and medius (the interscalene groove), over the first rib, behind the clavicle, and into the axilla around the axillary artery — and each location is the site of a named block. Fifth, the four classic ultrasound-guided approaches are interscalene (roots/trunks, shoulder surgery but with a high rate of phrenic-nerve block), supraclavicular (divisions, the whole upper limb, near the pleura), infraclavicular/costoclavicular (cords around the axillary artery, hand and forearm surgery) and axillary (branches, forearm and hand). Sixth, two birth-injury patterns localise damage: Erb's palsy (upper trunk C5-C6, the waiter's-tip posture) and Klumpke's palsy (lower trunk C8-T1, a claw hand and sometimes Horner syndrome). Built on the ultrasound-guided interscalene block study (Soor 2026), the diaphragm-sparing low-volume interscalene study (Verbeke 2026), the selective-trunk and supraclavicular block study (Rani 2026), the costoclavicular versus infraclavicular block study (Yazar 2026), the axillary-plexus-blockade study (Solomos 2025), the obstetric brachial-plexus-palsy study (Cimilli 2026), the musculocutaneous-nerve-variation study (Lv 2026), and the greater-auricular-nerve imaging study (Kabra 2026).
Practise this topic
On this page
Study tools
Your progress
Saved on this device.
Target exams
Red flags
- The brachial plexus is taught as a five-stage sequence: ROOTS (C5-T1 ventral rami) → TRUNKS (upper C5-6, middle C7, lower C8-T1) → DIVISIONS (anterior and posterior from each trunk) → CORDS (lateral, medial, posterior, named by relation to the axillary artery) → BRANCHES (musculocutaneous, axillary, radial, median, ulnar). Mnemonic: Read That Damn Cadaver.
- The five terminal branches and their cords: musculocutaneous and part of median (lateral cord); axillary and radial (posterior cord); ulnar and part of median (medial cord). The median nerve has contributions from BOTH the lateral and medial cords (the 'M' shape).
- The four classic US-guided block sites track the plexus along its course: interscalene (roots/trunks, shoulder, high phrenic-block risk), supraclavicular (divisions, the whole limb, pleural-puncture risk), infraclavicular/costoclavicular (cords, forearm/hand), axillary (branches, forearm/hand).
- The INTERSCALENE block predictably blocks the ipsilateral PHRENIC NERVE (C3-C5) in a high fraction of patients, causing hemidiaphragmatic paresis — avoid it in respiratory-compromised patients; low-volume or low-dose techniques reduce but do not abolish the risk.
- Erb's palsy is an UPPER-TRUNK (C5-C6) injury producing the 'waiter's tip' posture (arm adducted, internally rotated, elbow extended, forearm pronated, wrist flexed). Klumpke's palsy is a LOWER-TRUNK (C8-T1) injury producing a claw hand, sometimes with Horner syndrome if the T1 sympathetic fibres are involved.
- Anatomical VARIATION is common at the plexus — most notably the musculocutaneous nerve, which may pierce the coracobrachialis late or run with the median nerve (a communicating branch) — and ultrasound will identify these variants pre-procedure.
Meet the patient
A 68-year-old man with severe COPD (FEV1 forty per cent of predicted) presents for a shoulder hemiarthroplasty after a fall. Your consultant asks: "What block, and what is the one complication you must counsel him about?" The interscalene block covers the shoulder beautifully — but the phrenic nerve runs on scalenus anterior, and in this man hemidiaphragmatic paresis could mean ICU. Block choice is never just about coverage; it is about what sits next door. [1][2]
References8ShowHide
- [1]Soor B, et al. Ultrasound-guided Interscalene Block as a Safer Alternative to General Anesthesia in a Patient with Ankylosing Spondylitis Undergoing Proximal Humerus Fracture Fixation Ann Afr Med, 2026.PMID 42318963
- [2]Verbeke AL, et al. The diaphragm-sparing effect of interscalene block with a low-volume of ropivacaine 0.1% vs. 0.5%: A double-blind, controlled, randomised trial Eur J Anaesthesiol Intensive Care, 2026.PMID 42244823
- [3]Rani N, et al. Ultrasound-Guided Selective Trunk Block Combined With Supraclavicular Nerve Block for Awake Shoulder Arthroscopy: A Case Series Cureus, 2026.PMID 42220761
- [4]Yazar V, et al. Comparison of Costoclavicular Block and Infraclavicular Block Effects on Tissue Oxygen Saturation in Upper Extremity Surgery: A Randomized, Assessor-Blinded Controlled Trial Diagnostics (Basel), 2026.PMID 42279582
- [5]Solomos D, et al. Effect of Ketamine Supplementation in Axillary Plexus Blockade: A Comparative Study Cureus, 2025.PMID 41583169
- [6]Cimilli E, et al. Cognitive and Executive Function Profiles in School‑Age Children with Obstetric Brachial Plexus Injury Phys Occup Ther Pediatr, 2026.PMID 42322142
- [7]Lv Y, et al. An anatomical variation of the musculocutaneous nerve featuring early bifurcation and a transient common trunk with the median nerve: a case report Folia Morphol (Warsz), 2026.PMID 42345218
- [8]Kabra N, et al. Asymmetrical Brachial Plexus Involvement with Greater Auricular Nerve Involvement in Borderline Tuberculoid Leprosy: An Electrophysiological and Radiological Correlation Indian J Radiol Imaging, 2026.PMID 42344197