Anaes · Applied anatomy
Airway and larynx anatomy
Also known as Airway anatomy · Larynx anatomy · Laryngeal cartilages · Recurrent laryngeal nerve · Superior laryngeal nerve · Cricothyroid membrane
The airway is the anaesthetist's primary organ, and its anatomy underpins every act of intubation, laryngeal-mask placement, front-of-neck rescue and nerve block. The framework rests on six exam-critical ideas. First, the airway runs from the nose and mouth through the pharynx (nasopharynx, oropharynx, laryngopharynx) to the larynx and then the trachea, with the larynx sitting opposite the third to sixth cervical vertebrae. Second, the laryngeal skeleton is built from three single cartilages (thyroid, cricoid and epiglottis) and three paired cartilages (arytenoid, corniculate and cuneiform); the cricoid is the only complete ring of cartilage in the airway and is the key landmark for both the Sellick manoeuvre and a surgical airway. Third, the cricothyroid membrane stretches between the thyroid cartilage above and the cricoid below and is the target for emergency front-of-neck access (cricothyroidotomy). Fourth, the larynx is innervated by two branches of the vagus: the superior laryngeal nerve (whose internal branch is sensory to the larynx above the cords and whose external branch motor-innervates the cricothyroid, the tensor of the cords) and the recurrent laryngeal nerve (which is motor to all the other intrinsic muscles and sensory below the cords); damage to the recurrent laryngeal nerve paralyses a vocal cord in the paramedian position and causes hoarseness. Fifth, the trachea bifurcates at the carina into a right main bronchus that is wider, shorter and more vertical (the site of inadvertent right main-stem intubation and of aspiration) and a longer, narrower left main bronchus. Sixth, the paediatric airway differs structurally from the adult's — a relatively larger tongue and occiput, a higher, more anterior larynx (C3-C4 in the infant versus C6 in the adult), a large U-shaped epiglottis, and the narrowest point at the cricoid (not the vocal cords as in the adult) — which is why uncuffed tubes were traditionally used in young children and why the paediatric airway is more easily obstructed. Built on the larynx and cervical-trachea anatomy review (McCullagh 2022), the Difficult Airway Society 2015 guidelines (Frerk 2015), the CT cricothyroid-membrane-height study (Nutbeam 2017), the cricothyroid emergency-access review (Bribriesco 2018), the ultrasound front-of-neck-access review (Rai 2020), the recurrent-laryngeal-nerve paralysis review (Myssiorek 2004), the external-superior-laryngeal-nerve meta-analysis (Cheruiyot 2018), the intraoperative neural-monitoring guideline (Randolph 2011), the paediatric tracheobronchial-anatomy study (Tahir 2009), the paediatric airway-development review (Di Cicco 2021), the cuffed-versus-uncuffed-tube trial (Khine 1997), the paediatric neuromuscular-block review (Bonfiglio 2026), the IRIS cricoid-pressure trial (Birenbaum 2019), the bedside airway-assessment study (Eltrabily 2026), the endotracheal-tube-positioning study (Kufel 2026), the front-of-neck-access simulation study (Mullally 2026), and the superior-laryngeal-nerve-block case report (Chen 2026).
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- The CRICOID is the only complete ring of cartilage in the upper airway and the narrowest part of the paediatric airway — which is why uncuffed tubes were traditionally used in young children and why the cricoid is the anchor for both the Sellick manoeuvre and a surgical airway.
- The CRICOTHYROID MEMBRANE lies between the thyroid cartilage (above) and the cricoid (below) and is the target for emergency front-of-neck access (cricothyroidotomy) in a can't-intubate-can't-oxygenate situation.
- The RECURRENT LARYNGEAL NERVE (a branch of the vagus) is motor to all intrinsic laryngeal muscles EXCEPT cricothyroid, and sensory below the cords. Unilateral injury paralyses the cord in the paramedian position causing hoarseness; bilateral injury apposes both cords and can strangle the airway.
- The SUPERIOR LARYNGEAL NERVE has an internal branch (sensory to the larynx above the cords) and an external branch (motor to the cricothyroid, the tensor of the cords). External-branch injury weakens voice projection and high-pitched sound.
- The RIGHT MAIN BRONCHUS is wider, shorter and more vertical than the left, so an endotracheal tube passed too far, or an aspirated foreign body, preferentially enters the RIGHT main bronchus.
- The PAEDIATRIC airway differs from the adult's: a higher more anterior larynx (C3-C4 vs C6), a large U-shaped epiglottis, a relatively larger tongue and occiput, and the narrowest point at the CRICOID (not the cords).
Meet the patient
A 58-year-old man with a thick beard, short neck, and a BMI of 42 is listed for emergency laparotomy. He fasted six hours ago. Your consultant asks at the bedside: "If you cannot intubate and cannot oxygenate, where exactly do you cut?" The answer is the cricothyroid membrane — the Difficult Airway Society 2015 strategy reserves scalpel cricothyroidotomy for the point where tracheal intubation and supraglottic oxygenation have both failed with muscle relaxation and face-mask oxygenation impossible. But finding the membrane in this neck at three in the morning is the real test: ultrasound beats palpation for membrane localisation, especially in difficult neck anatomy. Every landmark you learn in this topic serves one purpose: locating that membrane before the patient desaturates. [2][5]
References17ShowHide
- [1]McCullagh KL, et al. Anatomy of the Larynx and Cervical Trachea. Neuroimaging Clin N Am, 2022.PMID 36244725
- [2]Frerk C, et al. Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults. Br J Anaesth, 2015.PMID 26556848
- [3]Nutbeam T, et al. The height of the cricothyroid membrane on computed tomography scans in trauma patients. Anaesthesia, 2017.PMID 28463474
- [4]Bribriesco A, et al. Cricothyroid Approach for Emergency Access to the Airway. Thorac Surg Clin, 2018.PMID 30054081
- [5]Rai Y, et al. The role of ultrasound in front-of-neck access for cricothyroid membrane identification: A systematic review. J Crit Care, 2020.PMID 32836091
- [6]Myssiorek D Recurrent laryngeal nerve paralysis: anatomy and etiology. Otolaryngol Clin North Am, 2004.PMID 15062685
- [7]Cheruiyot I, et al. Surgical anatomy of the external branch of the superior laryngeal nerve: a systematic review and meta-analysis. Langenbecks Arch Surg, 2018.PMID 30430230
- [8]Randolph GW, et al. Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: international standards guideline statement. Laryngoscope, 2011.PMID 21181860
- [9]Tahir N, et al. Tracheobronchial anatomy and the distribution of inhaled foreign bodies in children. Eur J Pediatr, 2009.PMID 18500537
- [10]Di Cicco M, et al. Structural and functional development in airways throughout childhood: Children are not small adults. Pediatr Pulmonol, 2021.PMID 33179415
- [11]Khine HH, et al. Comparison of cuffed and uncuffed endotracheal tubes in young children during general anesthesia. Anesthesiology, 1997.PMID 9066329
- [12]Bonfiglio R, et al. Neuromuscular block in paediatric patients undergoing airway management: a narrative review Curr Opin Anaesthesiol, 2026.PMID 41837392
- [13]Birenbaum A, et al. Effect of Cricoid Pressure Compared With a Sham Procedure in the Rapid Sequence Induction of Anesthesia: The IRIS Randomized Clinical Trial. JAMA Surg, 2019.PMID 30347104
- [14]Eltrabily H, et al. Improving bedside airway tests accuracy for predicting difficult laryngoscopy using ultrasound-measured skin-to-epiglottis distance J Anesth Analg Crit Care, 2026.PMID 42310819
- [15]Kufel J, et al. Detection, localization, and measurement of endotracheal tube positioning on adults' chest X-ray: developing a prediction model Sci Rep, 2026.PMID 42337351
- [16]Mullally ME, et al. Evaluation of novel materials for front-of-neck access simulations Anaesth Intensive Care, 2026.PMID 42290043
- [17]Chen M, et al. Ultrasound-Guided Superior Laryngeal Nerve Block Combined with Cricothyroid Membrane Puncture for Awake Tracheal Intubation in a Patient with a Laryngeal Tumor: A Case Report and Literature Review Int Med Case Rep J, 2026.PMID 42051408