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Anaes SAQsAirway management

Anaes SAQs · Airway management

Rapid sequence induction and modified RSI — preoxygenation, cricoid pressure debate, and the modern approach

The core RSI short-answer question — the principle (minimising the unprotected interval to protect against pulmonary aspiration), the indications (full stomach, pregnancy, bowel obstruction, trauma, delayed gastric emptying, the emergency and critical-care intubation), the seven-step classical sequence (preoxygenation, pre-treatment, induction, paralysis, no mask ventilation with cricoid pressure, intubation, confirmation and release), the cricoid pressure controversy (anatomical unreliability, impaired laryngoscopic view, airway obstruction, cervical spine movement; optional and released if interfering), and the modified RSI (gentle mask ventilation, reduced or omitted cricoid pressure, THRIVE high-flow nasal apnoeic oxygenation at 70 L per min, video laryngoscopy, rocuronium at RSI dose reversible by sugammadex 16 mg per kg), with the induction agent choice governed by haemodynamic reserve (reduce propofol or thiopental, or use ketamine or etomidate, with a vasopressor drawn up).

10 marks10 min4 min readSource-verified ·

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Prompt
Describe the rapid sequence induction (RSI) of anaesthesia. Include the indications, the seven-step classical sequence, the controversy around cricoid pressure, and the modifications that define the modern (modified) RSI. Outline your choice of induction agent and neuromuscular blocker in the haemodynamically unstable patient.

Question

Describe the rapid sequence induction (RSI) of anaesthesia. Include the indications, the seven-step classical sequence, the controversy around cricoid pressure, and the modifications that define the modern (modified) RSI. Outline your choice of induction agent and neuromuscular blocker in the haemodynamically unstable patient.

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References14ShowHide
  1. [1]Stolady D, Laviola M, Pillai A, et al. Effect of variable pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour: a modelling investigation. British journal of anaesthesia, 2021.PMID 33549319
  2. [2]Kumar J, et al. Cervical Spine Movements With Single-Handed Versus Bimanual Cricoid Pressure. J Neurosurg Anesthesiol, 2026.PMID 42333579
  3. [3]O'Connell DH, et al. Outcomes of Succinylcholine and Rocuronium for Rapid Sequence Intubation. West J Emerg Med, 2026.PMID 42258841
  4. [4]Freund Y, et al. Improving the safety of emergency tracheal intubation. Curr Opin Crit Care, 2026.PMID 42170830
  5. [5]Sheridan B, et al. Maintenance of prehospital anaesthesia using an intermittent bolus regime. Scand J Trauma Resusc Emerg Med, 2026.PMID 42351216
  6. [6]Ghaffar S, et al. Physiological difficult airway management in the emergency department. JPMA, 2026.PMID 42363338
  7. [7]Russotto V, et al. Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries (INTUBE). JAMA, 2021.PMID 33755076
  8. [8]Nimmagadda U, et al. Preoxygenation: Physiologic Basis, Benefits, and Potential Risks. Anesth Analg, 2017.PMID 28099321
  9. [9]Patel A, et al. Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). Anaesthesia, 2015.PMID 25388828
  10. [10]Lee C, et al. Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium. Anesthesiology, 2009.PMID 19387176
  11. [11]Meek T, et al. Cricoid pressure: can protective force be sustained? Br J Anaesth, 1998.PMID 9691875
  12. [12]Yentis SM Suxamethonium and hyperkalaemia. Anaesth Intensive Care, 1990.PMID 2186663
  13. [13]Mendelson CL The aspiration of stomach contents into the lungs during obstetric anesthesia. Am J Obstet Gynecol, 1946.PMID 20993766
  14. [14]Mushambi MC, Kinsella SM, Popat M, et al. Obstetric Anaesthetists' Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics. Anaesthesia, 2015.PMID 26449292
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