Anaes SAQs · Applied cardiovascular & respiratory physiology
RAAS and renal water/electrolyte handling
Primary — RAAS cascade (renin, ACE, angiotensin II, aldosterone); aldosterone sodium retention plus potassium and hydrogen excretion; ADH via osmoreceptors and aquaporin-2; countercurrent multiplier medullary gradient; natriuretic peptides; potassium handling; ACEi/ARB and aldosterone antagonist effects.
On this page
Study tools
Target exams
ANZCAFRCAABAEDAIC
Prompt
Describe the renin-angiotensin-aldosterone system and explain how the kidney regulates sodium, water and potassium balance.
Question
Describe the renin-angiotensin-aldosterone system and explain how the kidney regulates sodium, water and potassium balance.
[6]References4ShowHide
- [6]Adin D, et al. Influence of serum chloride concentrations on the renin-angiotensin-aldosterone system in dogs with congestive heart failure. Am J Physiol Renal Physiol, 2026.PMID 42324236
- [1]Xiong LI, et al. Sexual dimorphic pattern of renal transporters and channels in spontaneously hypertensive rats. Am J Physiol Cell Physiol, 2026.PMID 42290570
- [2]Drummond JB. Pathophysiology and aetiologies of hypernatremia. Best Pract Res Clin Endocrinol Metab, 2026.PMID 41176477
- [5]Wang Z, et al. Cardiovascular protection by SGLT2 inhibitors: an integrative review of mechanistic networks, clinical evidence, and safety considerations. Front Cardiovasc Med, 2026.PMID 42344351