Anaes SAQs · Postoperative nausea & vomiting
The PONV pathophysiology and the receptor targets
Primary — the 5-HT3, D2, NK1, H1, M1 receptors in the CTZ, NTS, vomiting centre; the ondansetron, droperidol, aprepitant, cyclizine, scopolamine; the multicomponent principle.
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ANZCAFRCAABAEDAIC
Prompt
Describe the pathophysiology of the PONV, including the key neurotransmitter receptors and the antiemetic agents that target them.
Question
Describe the pathophysiology of the PONV, including the key neurotransmitter receptors and the antiemetic agents that target them. (Question stem restated — the worked answers below carry the primary-source citations.)
References1ShowHide
- [1]Dombrower R, et al. Perioperative Anesthesia Strategies for the Prevention of Postoperative Nausea and Vomiting Within Enhanced Recovery After Surgery Pathways: A Clinical Narrative Review. J Clin Med, 2026.PMID 42194789