Anaes SAQs · Chronic & cancer pain
The pharmacological management of the neuropathic pain
Primary — the gabapentinoids (pregabalin, gabapentin — the alpha-2-delta ligands), the SNRIs (duloxetine), the TCAs (amitriptyline) as the first-line; the lidocaine patch, the capsaicin, the tramadol as the second; the combination of the different-mechanism agents; the renal dose-adjustment.
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Prompt
Describe the pharmacological management of the neuropathic pain, with the first- and the second-line agents and their adverse effects.
Question
Describe the pharmacological management of the neuropathic pain, with the first- and the second-line agents and their adverse effects.
References2ShowHide
- [1]Lu H, et al. Consensus on the clinical use of pregabalin in peripheral neuropathic pain. CNS Neurosci Ther, 2026.PMID 42310848
- [42310849]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.