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Anaes SAQsNeuroanaesthesia

Anaes SAQs · Neuroanaesthesia

The effect of the anaesthetic agents on the brain

Primary physiology — the IV agents reduce the CMRO2, the CBF, and the ICP (the neuroprotection); the volatiles increase the CBF and impair the autoregulation; the opioids have little direct effect; the ketamine myth debunked; the dexmedetomidine preserves the autoregulation.

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Prompt
Describe the effect of the common anaesthetic agents (the intravenous induction agents, the volatiles, the opioids, the muscle relaxants) on the cerebral blood flow, the metabolic rate, and the intracranial pressure.

Question

Describe the effect of the common anaesthetic agents (the intravenous induction agents, the volatiles, the opioids, the muscle relaxants) on the cerebral blood flow, the metabolic rate, and the intracranial pressure.

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You have read the opening of this SAQ. The complete unit — every section and its primary-source references — is part of the Anaesthesia fellowship library.

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References3ShowHide
  1. [1]Bou Sleiman V, et al. Anesthetic management of neurosurgical emergencies. Curr Opin Anaesthesiol, 2025.PMID 40071979
  2. [4]Haywood S, et al. Ketamine in acute brain injury: debunking the myth. Emerg Med Clin North Am, 2026.PMID 42342307
  3. [42342308]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
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