Anaes SAQs · Cardiac anaesthesia
Myocardial protection and cardioplegia
Final-examination SAQ for myocardial-protection-cardioplegia.
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Core facts. Anticoagulation per the verified STS/SCA/AmSECT targets — heparin 300 IU/kg fixed method, ACT 400-or-480 s surveyed thresholds, protamine at the surveyed 1:1 commonest ratio given slow — with TOE views named for weaning and regional assessment.
[8] [2]Topic structure. Cover hyperkalaemic diastolic arrest (taught mechanism), blood vs crystalloid and warm vs cold strategy choices, antegrade/retrograde delivery with the AR and RV caveats, single-shot del Nido/HTK evidence, TOE role, and the canonical crisis: Inadequate myocardial protection with difficulty weaning and regional wall-motion abnormality.
[4] [6] [2]Close. Disposition, ICU plan, and common traps.
[4]References8ShowHide
- [1]Mazer CD, Whitlock RP, Fergusson DA, et al. Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery (TRICS III). New England Journal of Medicine, 2017.PMID 29130845
- [2]Hahn RT, Abraham T, Adams MS, et al. Guidelines for performing a comprehensive transesophageal echocardiographic examination: recommendations from the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists. Journal of the American Society of Echocardiography, 2013.PMID 23998692
- [3]Levy JH, et al. What's fishy about protamine? Clinical use, adverse reactions, and potential alternatives. Journal of Thrombosis and Haemostasis, 2023.PMID 37062523
- [4]An KR, Rahman IA, Tam DY, et al. A Systematic Review and Meta-Analysis of del Nido Versus Conventional Cardioplegia in Adult Cardiac Surgery. Innovations (Phila), 2019.PMID 31347414
- [5]Albadrani M Histidine-tryptophan-ketoglutarate solution versus multidose cardioplegia for myocardial protection in cardiac surgeries: a systematic review and meta-analysis. Journal of Cardiothoracic Surgery, 2022.PMID 35642063
- [6]Derryberry S, Tribble C In Through the Out Door: Tips and Tricks for Giving Retrograde Cardioplegia. Heart Surgery Forum, 2018.PMID 30084786
- [7]James TM, Nores M, Rousou JA, et al. Warm Blood Cardioplegia for Myocardial Protection: Concepts and Controversies. Texas Heart Institute Journal, 2020.PMID 32603472
- [8]Shore-Lesserson L, Baker RA, Ferraris V, et al. STS/SCA/AmSECT Clinical Practice Guidelines: Anticoagulation during Cardiopulmonary Bypass. Journal of Extra-Corporeal Technology, 2018.PMID 29559750