Anaes SAQs · Local anaesthetic pharmacology
Local anaesthetic systemic toxicity
Short-answer question on local-anaesthetic maximum doses, toxicity determinants and LAST management.
On this page
Study tools
Target exams
ANZCAFRCAABAEDAICFCAIFCA_SA
Prompt
Outline the maximum safe doses of the common local anaesthetics, the factors that determine systemic toxicity, and the management of local-anaesthetic systemic toxicity (LAST).
Question
Outline the maximum safe doses of the common local anaesthetics, the factors that determine systemic toxicity, and the management of local-anaesthetic systemic toxicity (LAST).
[2]References2ShowHide
- [1]Christensen SA, Shipp EM. MaxSafe: a mobile-friendly calculator for fractional local anesthetic toxicity and epinephrine dose tracking in dental practice. J Dent Anesth Pain Med, 2026.PMID 42266421
- [2]Meral RM, Nagpal AS, Wasserman R. International Pain and Spine Intervention Society Emergency Protocols: Local Anesthetic Systemic Toxicity (LAST). Interv Pain Med, 2026.PMID 42325878