Anaes SAQs · Applied cardiovascular & respiratory physiology
Carbon dioxide transport
Primary — three forms (bicarbonate 90 percent, carbamino 5 percent, dissolved 5 percent); carbonic anhydrase and the chloride shift; near-linear CO2 curve in physiological ranges; Haldane effect; haemoglobin buffering; venous-to-arterial gap as perfusion marker.
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ANZCAFRCAABAEDAIC
Prompt
Describe how carbon dioxide is transported in the blood. Explain the Haldane effect and the chloride shift, and the shape of the CO2 dissociation curve.
Question
Describe how carbon dioxide is transported in the blood. Explain the Haldane effect and the chloride shift, and the shape of the CO2 dissociation curve.[2]
References2ShowHide
- [1]O'Neill DP, Robbins PA. A mechanistic physicochemical model of carbon dioxide transport in blood. J Appl Physiol, 2017.PMID 27881667
- [2]Mallat J, Jozwiak M, et al. Use of CO(2)-derived variables in critically ill patients. Ann Intensive Care, 2025.PMID 40999252