Anaes SAQs · Anaesthetic adjuncts

The benzodiazepines in anaesthesia

Final SAQ — the class mechanism (the GABA-A positive allosteric modulator; the alpha-gamma interface; the FREQUENCY not the DURATION; the ceiling effect); the four agents (midazolam rapid/short/active metabolite; diazepam slow/long/nordiazepam; lorazepam slow/long/no active metabolite — the drug of status epilepticus; remimazolam ultra-short/ester-hydrolysed/constant CSHT); the pharmacodynamics (anxiolysis, sedation, anterograde amnesia, anticonvulsant, synergistic respiratory depression with the opioid); the flumazenil antagonist (competitive; shorter half-life — the resedation; the seizure risk in the chronic user).