Anaes SAQs · Anaesthetic adjuncts
Alfentanil pharmacology
Short-answer question on alfentanil pharmacokinetics, its rapid onset, and comparison with fentanyl and remifentanil.
On this page
Study tools
Target exams
ANZCAFRCAABAEDAICFCAIFCA_SA
Prompt
Describe the pharmacokinetics of alfentanil, explain why it has the fastest onset of the fentanyl family, and compare it with fentanyl and remifentanil.
Question
Describe the pharmacokinetics of alfentanil, explain why it has the fastest onset of the fentanyl family, and compare it with fentanyl and remifentanil [1][2].
References4ShowHide
- [1]Moman RN, et al. Alfentanil. StatPearls, 2024.PMID 29261876
- [2]Shafer SL, et al. Pharmacokinetics, pharmacodynamics, and rational opioid selection. Anesthesiology, 1991.PMID 1824743
- [3]Hughes MA, et al. Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs. Anesthesiology, 1992.PMID 1539843
- [4]Beers R, et al. Remifentanil update: clinical science and utility. CNS Drugs, 2004.PMID 15581380