Acute Liver Failure — King's College criteria, and the three parallel decisions

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Acute liver failure (ALF) is severe acute liver injury with coagulopathy (INR at least 1.5) and any degree of hepatic encephalopathy, developing within 26 weeks in a patient without pre-existing cirrhosis (Wilson's disease and reactivation of chronic hepatitis B are the accepted exceptions). Full topic, figures, and citations: https://medvellum.com/topics/acute-liver-failure Chapters 00:00 The one-line answer 01:11 Meet the patient 02:06 Red flags 02:59 Classification — by time and by cause, both prognostic 04:16 How common, and the aetiological mix is strongly regional 06:33 Why patients di…

• Duration 1:16Acute Liver Failure — The seven pearls that decide an acute liver failure answer5 Sept 2026