Prompt

Examiner places cards: valproate, lithium, lamotrigine, sertraline, olanzapine, diazepam. A blank counselling grid asks untreated illness risk, first-trimester MCM, third-trimester neonate, lactation. Name Grote, Viguera, Huybrechts, Patorno, EURAP/NEAD, Grigoriadis, Bergink within the station.

Station structure

Time: 8–10 minutes. Depth: consultant teaching registrar. Expect absolute-risk language, named datasets, and a four-verb plan (continue / switch / stop / dose-adjust).^[2]^[4]

References8Show

[1]Grote NK, Bridge JA, Gavin AR, et al. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction Arch Gen Psychiatry, 2010.PMID 20921117
[2]Viguera AC, Whitfield T, Baldessarini RJ, et al. Risk of recurrence in women with bipolar disorder during pregnancy: prospective study of mood stabilizer discontinuation Am J Psychiatry, 2007.PMID 18056236
[3]Huybrechts KF, Hernández-Díaz S, Avorn J, et al. Antidepressant use in pregnancy and the risk of cardiac defects N Engl J Med, 2014.PMID 25229932
[4]Patorno E, Huybrechts KF, Bateman BT, et al. Lithium Use in Pregnancy and the Risk of Cardiac Malformations N Engl J Med, 2017.PMID 28591541
[5]Tomson T, Battino D, Bonizzoni E, et al. Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry Lancet Neurol, 2011.PMID 21652013
[6]Meador KJ, Baker GA, Browning N, et al. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs N Engl J Med, 2009.PMID 19369666
[7]Grigoriadis S, VonderPorten EH, Mamisashvili L, et al. The effect of prenatal antidepressant exposure on neonatal adaptation: a systematic review and meta-analysis J Clin Psychiatry, 2013.PMID 23656856
[8]Bergink V, Rasgon N, Wisner KL Postpartum Psychosis: Madness, Mania, and Melancholia in Motherhood Am J Psychiatry, 2016.PMID 27609245

Station structure

Time: 8–10 minutes. Depth: consultant teaching registrar. Expect absolute-risk language, named datasets, and a four-verb plan (continue / switch / stop / dose-adjust).^[2]^[4]

References8Show

[1]Grote NK, Bridge JA, Gavin AR, et al. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction Arch Gen Psychiatry, 2010.PMID 20921117
[2]Viguera AC, Whitfield T, Baldessarini RJ, et al. Risk of recurrence in women with bipolar disorder during pregnancy: prospective study of mood stabilizer discontinuation Am J Psychiatry, 2007.PMID 18056236
[3]Huybrechts KF, Hernández-Díaz S, Avorn J, et al. Antidepressant use in pregnancy and the risk of cardiac defects N Engl J Med, 2014.PMID 25229932
[4]Patorno E, Huybrechts KF, Bateman BT, et al. Lithium Use in Pregnancy and the Risk of Cardiac Malformations N Engl J Med, 2017.PMID 28591541
[5]Tomson T, Battino D, Bonizzoni E, et al. Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry Lancet Neurol, 2011.PMID 21652013
[6]Meador KJ, Baker GA, Browning N, et al. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs N Engl J Med, 2009.PMID 19369666
[7]Grigoriadis S, VonderPorten EH, Mamisashvili L, et al. The effect of prenatal antidepressant exposure on neonatal adaptation: a systematic review and meta-analysis J Clin Psychiatry, 2013.PMID 23656856
[8]Bergink V, Rasgon N, Wisner KL Postpartum Psychosis: Madness, Mania, and Melancholia in Motherhood Am J Psychiatry, 2016.PMID 27609245

Perinatal psychopharmacology viva — hierarchy, signals, shared decision

Station structure

Perinatal psychopharmacology viva — hierarchy, signals, shared decision

Station structure