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Psych VivasConsultation-liaison psychiatry

Psych Vivas · Consultation-liaison psychiatry

Endocrine psychiatry — structured clinical viva

Fellowship viva on thyroid/Cushing/Addison/steroid psychiatry, crisis priorities, bridge psychotropics, and lithium–thyroid monitoring.

clinical1 min readVerification in progress

Target exams

FRANZCPMRCPsychABPNMD-DNB
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Target exams

FRANZCPMRCPsychABPNMD-DNB
Prompt
You are the CL psychiatry registrar. Three consultations today: (1) a woman with newly confirmed Cushing disease and severe depression with passive death wishes; (2) a man day 3 after high-dose prednisolone for vasculitis who is sleepless, irritable, and grandiose; (3) a lithium-treated bipolar patient with no thyroid labs for 4 years who now has weight gain and low mood. Structure your approach across syndrome map, investigations, crisis rules (including Addison/AI), steroid algorithm, lithium–thyroid, and residual prognosis after endocrine correction.

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Interpretation

Reveal interpretationShowHide

Open with an axis map, not one label. Cover thyroid excess/deficiency (including myxoedema psychosis as rare extreme), Cushing neuropsychiatry, adrenal insufficiency/crisis, and exogenous steroid toxicity as distinct drivers that can coexist with primary psychiatric illness.[1][4][7][8]

Case 1 — Cushing depression. Name major depression as the dominant comorbidity in classic series; assess suicide risk; prioritise definitive hypercortisolism treatment with endocrine/neurosurgery pathways; use antidepressants as adjuncts only; warn that residual mood/cognition can persist after cure.[3][4]

Case 2 — Steroid mania/psychosis. Temporal link to high-dose prednisolone; Warrington/Dubovsky framing; reduce steroids if medically allowed; short-term low-dose antipsychotic for danger; avoid lifelong bipolar label from a single episode.[1][2]

Case 3 — Lithium–thyroid. Check TSH/free T4 now; educate that lithium causes hypothyroidism commonly and hyperthyroidism in an under-recognised systematic-review association; co-manage replacement or further endocrine work-up.[6][7]

Crisis pearl. If any stem turns into Addison crisis (shock, hyponatraemia, delirium), state parenteral hydrocortisone and fluids first per Endocrine Society guidance.[5]

Close. Shared care, capacity during organic states, and longitudinal diagnostic humility after endocrine correction.[1][4][5]

References8ShowHide
  1. [1]Warrington TP, Bostwick JM Psychiatric adverse effects of corticosteroids Mayo Clin Proc, 2006.PMID 17036562
  2. [2]Dubovsky AN, Arvikar S, Stern TA, et al. The neuropsychiatric complications of glucocorticoid use: steroid psychosis revisited Psychosomatics, 2012.PMID 22424158
  3. [3]Sonino N, Fava GA, Raffi AR, et al. Clinical correlates of major depression in Cushing's disease Psychopathology, 1998.PMID 9780396
  4. [4]Pivonello R, Simeoli C, De Martino MC, et al. Neuropsychiatric disorders in Cushing's syndrome Front Neurosci, 2015.PMID 25941467
  5. [5]Bornstein SR, Allolio B, Arlt W, et al. Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline J Clin Endocrinol Metab, 2016.PMID 26760044
  6. [6]Fairbrother F, Petzl N, Scott JG, et al. Lithium can cause hyperthyroidism as well as hypothyroidism: A systematic review of an under-recognised association Aust N Z J Psychiatry, 2019.PMID 30841715
  7. [7]Feldman AZ, Shrestha RT, Hennessey JV Neuropsychiatric manifestations of thyroid disease Endocrinol Metab Clin North Am, 2013.PMID 24011880
  8. [8]Krüger J, Kraschewski A, Jockers-Scherübl MC Myxedema Madness - Systematic literature review of published case reports Gen Hosp Psychiatry, 2021.PMID 34419786
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