Skip to main content
MedVellum
QuestionsVideosPricing

MedVellum

Fellowship exam preparation across every specialty: source-verified topics, questions in every format, and videos.

Product

  • Specialties
  • Questions
  • Videos
  • Exam tools
  • Pricing

Verification & policy

  • Verified register
  • Editorial policy
  • Privacy
  • Terms

Account

  • Sign in
  • Create account
  • Dashboard
  • Account & billing

© 2026 MedVellum. For education only — not a substitute for clinical judgement.

llms.txtPsychiatry LLM catalogSitemap

Psych TopicsOld age psychiatry — psychotropic prescribing

Psych · Old age psychiatry — psychotropic prescribing

Prescribing psychotropics in older adults

Also known as Geriatric psychopharmacology · Psychotropics in the elderly · Beers criteria psychotropics · STOPP START psychiatry · Start low go slow · Antipsychotics black box dementia · Geriatric prescribing safety

Exam-exhaustive fellowship reference on prescribing psychotropics in older adults — age-related PK/PD, Beers and STOPP/START, start-low-go-slow-but-go, antipsychotic mortality/stroke black-box in dementia, QTc, falls, SIADH, anticholinergic burden, class-specific dosing and monitoring, deprescribing. FRANZCP-primary, globally tagged.

high20 referencesUpdated 26 July 202611 min readVerification in progress

Practise this topic

  • 10 MCQs

Your progress

Saved on this device.

Practise this topic10 MCQs with explanations

Target exams

FRANZCPMRCPsychABPNMD-DNBNEET-SS

Red flags

  • New antipsychotic for dementia-related psychosis or agitation without documented target symptom, non-drug trial, or review/stop date — mortality and stroke risk
  • Syncope or near-syncope on QT-prolonging psychotropics with stacked risk factors — treat as possible TdP until proven otherwise
  • Acute confusion, falls, or seizures after SSRI/SNRI start — check sodium urgently for SIADH
  • Typical antipsychotic (or any high-potency neuroleptic) in suspected dementia with Lewy bodies — extreme neuroleptic sensitivity
  • Chronic benzodiazepine or Z-drug in frail older adult with recurrent falls — deprescribe plan mandatory
  • Start-low-stay-low under-treatment of severe late-life depression with high suicide lethality
On this page
Study tools

Your progress

Saved on this device.

Practise this topic10 MCQs with explanations

Target exams

FRANZCPMRCPsychABPNMD-DNBNEET-SS

Red flags

  • New antipsychotic for dementia-related psychosis or agitation without documented target symptom, non-drug trial, or review/stop date — mortality and stroke risk
  • Syncope or near-syncope on QT-prolonging psychotropics with stacked risk factors — treat as possible TdP until proven otherwise
  • Acute confusion, falls, or seizures after SSRI/SNRI start — check sodium urgently for SIADH
  • Typical antipsychotic (or any high-potency neuroleptic) in suspected dementia with Lewy bodies — extreme neuroleptic sensitivity
  • Chronic benzodiazepine or Z-drug in frail older adult with recurrent falls — deprescribe plan mandatory
  • Start-low-stay-low under-treatment of severe late-life depression with high suicide lethality
The one-line answer

Prescribe for older adults with eyes open to altered PK and PD, polypharmacy and frailty. Apply Beers and STOPP/START thinking, start low and go slow but treat to a therapeutic dose, prioritise non-drug care for BPSD, reserve short-course low-dose antipsychotics for severe risk because the mortality and stroke signals are real, monitor sodium, QTc and falls, and always write a review or deprescribing plan.[1][2][4][5]

Meet the patient

A frail 86-year-old in residential care is on nine regular medicines, including oxybutynin for urgency, diazepam "for nerves" for thirty years, quetiapine 25 mg "for sleep", and last month a GP added citalopram 20 mg for low mood. She has fallen three times this week and is now confused.[2][17][18]

Her sodium is 124 mmol/L, her QTc is 490 ms, and her anticholinergic burden score is off the page. Across the bay, an under-dosed 70-year-old with severe melancholic depression sits silently with a stockpile of paracetamol because his sertraline has never been titrated past 25 mg.[16][20]

The exam question that owns this topic: what exactly is wrong with both charts, and what will you do about it tonight? The first patient is over-sedated into harm; the second is under-treated into danger. Geriatric prescribing is the art of avoiding both.[1][5]

Psychiatry Fellowship Pro

Continue reading

You have read the opening of this topic. The complete unit — every section and its primary-source references — is part of the Psychiatry Fellowship fellowship library.

Sign in to continueSee pricing
References20ShowHide
  1. [1]Mangoni AA, Jackson SHD Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications Br J Clin Pharmacol, 2004.PMID 14678335
  2. [2]By the 2023 American Geriatrics Society Beers Criteria Update Expert Panel American Geriatrics Society 2023 updated AGS Beers Criteria for potentially inappropriate medication use in older adults J Am Geriatr Soc, 2023.PMID 37139824
  3. [3]By the 2019 American Geriatrics Society Beers Criteria Update Expert Panel American Geriatrics Society 2019 Updated AGS Beers Criteria for Potentially Inappropriate Medication Use in Older Adults J Am Geriatr Soc, 2019.PMID 30693946
  4. [4]O'Mahony D, O'Sullivan D, Byrne S, O'Connor MN, Ryan C, Gallagher P STOPP/START criteria for potentially inappropriate prescribing in older people: version 2 Age Ageing, 2015.PMID 25324330
  5. [5]Schneider LS, Dagerman KS, Insel P Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials JAMA, 2005.PMID 16234500
  6. [6]Schneider LS, Tariot PN, Dagerman KS, Davis SM, Hsiao JK, Ismail MS, et al. Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease N Engl J Med, 2006.PMID 17035647
  7. [7]Gill SS, Bronskill SE, Normand SL, Anderson GM, Sykora K, Lam K, et al. Antipsychotic drug use and mortality in older adults with dementia Ann Intern Med, 2007.PMID 17548409
  8. [8]Wooltorton E Risperidone (Risperdal): increased rate of cerebrovascular events in dementia trials CMAJ, 2002.PMID 12451085
  9. [9]Ballard C, Lana MM, Theodoulou M, Douglas S, McShane R, Jacoby R, et al. A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics (the DART-AD trial) PLoS Med, 2008.PMID 18384230
  10. [10]Ballard C, Hanney ML, Theodoulou M, Douglas S, McShane R, Kossakowski K, et al. The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial Lancet Neurol, 2009.PMID 19138567
  11. [11]Devanand DP, Mintzer J, Schultz SK, Andrews HF, Sultzer DL, de la Pena D, et al. Relapse risk after discontinuation of risperidone in Alzheimer's disease N Engl J Med, 2012.PMID 23075176
  12. [12]Ray WA, Chung CP, Murray KT, Hall K, Stein CM Atypical antipsychotic drugs and the risk of sudden cardiac death N Engl J Med, 2009.PMID 19144938
  13. [13]Glassman AH, Bigger JT Jr Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death Am J Psychiatry, 2001.PMID 11691681
  14. [14]Reilly JG, Ayis SA, Ferrier IN, Jones SJ, Thomas SH QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients Lancet, 2000.PMID 10744090
  15. [15]Funk MC, Beach SR, Bostwick JR, et al. QTc Prolongation and Psychotropic Medications Am J Psychiatry, 2020.PMID 32114782
  16. [16]Fabian TJ, Amico JA, Kroboth PD, Mulsant BH, Corey SE, Begley AE, et al. Paroxetine-induced hyponatremia in older adults: a 12-week prospective study Arch Intern Med, 2004.PMID 14769630
  17. [17]Glass J, Lanctôt KL, Herrmann N, Sproule BA, Busto UE Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits BMJ, 2005.PMID 16284208
  18. [18]Woolcott JC, Richardson KJ, Wiens MO, Patel B, Marin J, Khan KM, Marra CA Meta-analysis of the impact of 9 medication classes on falls in elderly persons Arch Intern Med, 2009.PMID 19933955
  19. [19]Maher AR, Maglione M, Bagley S, Suttorp M, Hu JH, Ewing B, et al. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis JAMA, 2011.PMID 21954480
  20. [20]Malhi GS, Bell E, Bassett D, Boyce P, Bryant R, Hazell P, et al. The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders Aust N Z J Psychiatry, 2021.PMID 33353391

Test yourself

Practise what you just read

  • 10 MCQs
Psychiatry Fellowship Pro

$29/ monthor $279 / year

The complete Psychiatry Fellowship library, every exam format, one subscription.

  • Complete library for one chosen specialty
  • Timed MCQ mock exams and spaced review
  • Clinical cases & cross-table vivas
See pricingSign in
PreviousPremenstrual dysphoric disorderGeneral adult psychiatry — mood disorders / women's mental healthNextPrevention and early intervention in mental healthFoundations — prevention and early intervention