Psych · General adult psychiatry — OCRD / BFRB
Trichotillomania and excoriation disorder
Also known as Hair-pulling disorder · Skin-picking disorder · Pathologic skin picking · Dermatillomania · BFRB · Body-focused repetitive behaviour · Neurotic excoriation · OCRD
Exam-exhaustive fellowship reference on trichotillomania and excoriation (skin-picking) disorder — DSM-5-TR OCRD criteria; automatic vs focused styles; differentials vs alopecia areata and OCD/BDD; MGH-HPS/SPS; habit reversal training and ComB/ACT-enhanced BT; adult NAC RCTs (Grant 2009/2016) vs paediatric NAC null (Bloch); limited SSRI signal; clomipramine and olanzapine specialist options; trichobezoar and infection emergencies. FRANZCP-primary, globally tagged.
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Target exams
Red flags
- Trichophagia with abdominal pain, vomiting, or obstruction signs — consider trichobezoar/Rapunzel syndrome and urgent surgical/GI pathway
- Cellulitis, abscess, or systemic sepsis from extensive skin picking — medical/surgical toilet and antibiotics
- Active suicidal ideation with comorbid depression or severe shame-driven isolation — full risk assessment and safety plan
- Rapid tissue destruction, scarring risk to eyes/eyelids, or self-surgery attempts — escalate intensity of care
- New late-onset picking with pruritus or neurologic signs — do not assume idiopathic BFRB; exclude medical dermatoses and organic disease
- Stimulant or other substance-associated picking exacerbation without review of regimen
Meet the patient
A 28-year-old teacher is referred by dermatology for "non-healing facial acne". Six months of antibiotics have not touched it. She pulls her scalp hair while marking essays and picks her chin on video calls — both outside her full awareness until she sees the blood. She swallows some of the hairs. She is ashamed, has stopped swimming, and her mood is sinking.[7][12]
Two exam questions are now live, and you must answer both: what is this, and what is the first treatment? and what will kill her if you do not ask? Everything below is the consultant-level answer to those two questions.[1][12]
References14ShowHide
- [1]Grant JE, Odlaug BL, Kim SW N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study Arch Gen Psychiatry, 2009.PMID 19581567
- [2]Bloch MH, Panza KE, Grant JE, et al. N-Acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial J Am Acad Child Adolesc Psychiatry, 2013.PMID 23452680
- [3]Grant JE, Chamberlain SR, Redden SA, et al. N-Acetylcysteine in the Treatment of Excoriation Disorder: A Randomized Clinical Trial JAMA Psychiatry, 2016.PMID 27007062
- [4]McGuire JF, Ung D, Selles RR, et al. Treating trichotillomania: a meta-analysis of treatment effects and moderators for behavior therapy and serotonin reuptake inhibitors J Psychiatr Res, 2014.PMID 25108618
- [5]Farhat LC, Olfson E, Nasir M, et al. Pharmacological and behavioral treatment for trichotillomania: An updated systematic review with meta-analysis Depress Anxiety, 2020.PMID 32390221
- [6]Christenson GA, Pyle RL, Mitchell JE Estimated lifetime prevalence of trichotillomania in college students J Clin Psychiatry, 1991.PMID 1938977
- [7]Grant JE, Dougherty DD, Chamberlain SR Prevalence, gender correlates, and co-morbidity of trichotillomania Psychiatry Res, 2020.PMID 32334275
- [8]Swedo SE, Leonard HL, Rapoport JL, et al. A double-blind comparison of clomipramine and desipramine in the treatment of trichotillomania (hair pulling) N Engl J Med, 1989.PMID 2761586
- [9]Woods DW, Wetterneck CT, Flessner CA A controlled evaluation of acceptance and commitment therapy plus habit reversal for trichotillomania Behav Res Ther, 2006.PMID 16039603
- [10]Van Ameringen M, Mancini C, Patterson B, et al. A randomized, double-blind, placebo-controlled trial of olanzapine in the treatment of trichotillomania J Clin Psychiatry, 2010.PMID 20441724
- [11]Carlson EJ, Malloy EJ, Brauer L, et al. Comprehensive Behavioral (ComB) Treatment of Trichotillomania: A Randomized Clinical Trial Behav Ther, 2021.PMID 34656205
- [12]Grant JE, Chamberlain SR Trichotillomania and Skin-Picking Disorder: An Update Focus (Am Psychiatr Publ), 2021.PMID 35747295
- [13]Grant JE, Chamberlain SR Prevalence of skin picking (excoriation) disorder J Psychiatr Res, 2020.PMID 32781374
- [14]Lee DK, Lipner SR The Potential of N-Acetylcysteine for Treatment of Trichotillomania, Excoriation Disorder, Onychophagia, and Onychotillomania: An Updated Literature Review Int J Environ Res Public Health, 2022.PMID 35681955