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Psych TopicsGeneral adult psychiatry — OCRD / BFRB

Psych · General adult psychiatry — OCRD / BFRB

Trichotillomania and excoriation disorder

Also known as Hair-pulling disorder · Skin-picking disorder · Pathologic skin picking · Dermatillomania · BFRB · Body-focused repetitive behaviour · Neurotic excoriation · OCRD

Exam-exhaustive fellowship reference on trichotillomania and excoriation (skin-picking) disorder — DSM-5-TR OCRD criteria; automatic vs focused styles; differentials vs alopecia areata and OCD/BDD; MGH-HPS/SPS; habit reversal training and ComB/ACT-enhanced BT; adult NAC RCTs (Grant 2009/2016) vs paediatric NAC null (Bloch); limited SSRI signal; clomipramine and olanzapine specialist options; trichobezoar and infection emergencies. FRANZCP-primary, globally tagged.

medium14 referencesUpdated 26 July 202613 min readVerification in progress

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Target exams

FRANZCPMRCPsychABPNMD-DNBNEET-SS

Red flags

  • Trichophagia with abdominal pain, vomiting, or obstruction signs — consider trichobezoar/Rapunzel syndrome and urgent surgical/GI pathway
  • Cellulitis, abscess, or systemic sepsis from extensive skin picking — medical/surgical toilet and antibiotics
  • Active suicidal ideation with comorbid depression or severe shame-driven isolation — full risk assessment and safety plan
  • Rapid tissue destruction, scarring risk to eyes/eyelids, or self-surgery attempts — escalate intensity of care
  • New late-onset picking with pruritus or neurologic signs — do not assume idiopathic BFRB; exclude medical dermatoses and organic disease
  • Stimulant or other substance-associated picking exacerbation without review of regimen
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Your progress

Saved on this device.

Practise this topic10 MCQs with explanations

Target exams

FRANZCPMRCPsychABPNMD-DNBNEET-SS

Red flags

  • Trichophagia with abdominal pain, vomiting, or obstruction signs — consider trichobezoar/Rapunzel syndrome and urgent surgical/GI pathway
  • Cellulitis, abscess, or systemic sepsis from extensive skin picking — medical/surgical toilet and antibiotics
  • Active suicidal ideation with comorbid depression or severe shame-driven isolation — full risk assessment and safety plan
  • Rapid tissue destruction, scarring risk to eyes/eyelids, or self-surgery attempts — escalate intensity of care
  • New late-onset picking with pruritus or neurologic signs — do not assume idiopathic BFRB; exclude medical dermatoses and organic disease
  • Stimulant or other substance-associated picking exacerbation without review of regimen
The one-line answer

Trichotillomania and excoriation disorder are obsessive-compulsive and related body-focused repetitive behaviours — managed first with habit-reversal-based behaviour therapy (HRT, ComB, ACT-enhanced packages), with adult N-acetylcysteine 1200–2400 mg/day as the best-supported drug, a weak SSRI signal for the core behaviour unlike classic OCD, and a surgical alert for trichobezoar after trichophagia. Adult NAC does not generalise to children.[1][3][4][5][12]

Meet the patient

A 28-year-old teacher is referred by dermatology for "non-healing facial acne". Six months of antibiotics have not touched it. She pulls her scalp hair while marking essays and picks her chin on video calls — both outside her full awareness until she sees the blood. She swallows some of the hairs. She is ashamed, has stopped swimming, and her mood is sinking.[7][12]

Two exam questions are now live, and you must answer both: what is this, and what is the first treatment? and what will kill her if you do not ask? Everything below is the consultant-level answer to those two questions.[1][12]

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References14ShowHide
  1. [1]Grant JE, Odlaug BL, Kim SW N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study Arch Gen Psychiatry, 2009.PMID 19581567
  2. [2]Bloch MH, Panza KE, Grant JE, et al. N-Acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial J Am Acad Child Adolesc Psychiatry, 2013.PMID 23452680
  3. [3]Grant JE, Chamberlain SR, Redden SA, et al. N-Acetylcysteine in the Treatment of Excoriation Disorder: A Randomized Clinical Trial JAMA Psychiatry, 2016.PMID 27007062
  4. [4]McGuire JF, Ung D, Selles RR, et al. Treating trichotillomania: a meta-analysis of treatment effects and moderators for behavior therapy and serotonin reuptake inhibitors J Psychiatr Res, 2014.PMID 25108618
  5. [5]Farhat LC, Olfson E, Nasir M, et al. Pharmacological and behavioral treatment for trichotillomania: An updated systematic review with meta-analysis Depress Anxiety, 2020.PMID 32390221
  6. [6]Christenson GA, Pyle RL, Mitchell JE Estimated lifetime prevalence of trichotillomania in college students J Clin Psychiatry, 1991.PMID 1938977
  7. [7]Grant JE, Dougherty DD, Chamberlain SR Prevalence, gender correlates, and co-morbidity of trichotillomania Psychiatry Res, 2020.PMID 32334275
  8. [8]Swedo SE, Leonard HL, Rapoport JL, et al. A double-blind comparison of clomipramine and desipramine in the treatment of trichotillomania (hair pulling) N Engl J Med, 1989.PMID 2761586
  9. [9]Woods DW, Wetterneck CT, Flessner CA A controlled evaluation of acceptance and commitment therapy plus habit reversal for trichotillomania Behav Res Ther, 2006.PMID 16039603
  10. [10]Van Ameringen M, Mancini C, Patterson B, et al. A randomized, double-blind, placebo-controlled trial of olanzapine in the treatment of trichotillomania J Clin Psychiatry, 2010.PMID 20441724
  11. [11]Carlson EJ, Malloy EJ, Brauer L, et al. Comprehensive Behavioral (ComB) Treatment of Trichotillomania: A Randomized Clinical Trial Behav Ther, 2021.PMID 34656205
  12. [12]Grant JE, Chamberlain SR Trichotillomania and Skin-Picking Disorder: An Update Focus (Am Psychiatr Publ), 2021.PMID 35747295
  13. [13]Grant JE, Chamberlain SR Prevalence of skin picking (excoriation) disorder J Psychiatr Res, 2020.PMID 32781374
  14. [14]Lee DK, Lipner SR The Potential of N-Acetylcysteine for Treatment of Trichotillomania, Excoriation Disorder, Onychophagia, and Onychotillomania: An Updated Literature Review Int J Environ Res Public Health, 2022.PMID 35681955

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