Psych · General adult psychiatry — somatic symptom and related
Illness anxiety disorder
Also known as Health anxiety · Hypochondriasis · Hypochondriacal disorder · Illness anxiety · Cyberchondria · Disease phobia · IAD
Exam-exhaustive fellowship reference on illness anxiety disorder — DSM-5-TR criteria and care-seeking/care-avoidant subtypes; DSM-IV hypochondriasis reorganisation vs somatic symptom disorder; ICD-11 hypochondriasis framing; Warwick–Salkovskis CBT model; epidemiology and mortality risk; differentials; CL interface; CBT evidence (Barsky, Greeven, CHAMP, meta-analyses, internet CBT); SSRI evidence (paroxetine, fluoxetine). FRANZCP-primary, globally tagged.
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Red flags
- Active suicidal ideation, intent or plan — hypochondriasis cohorts show elevated suicide and all-cause mortality; same-day risk assessment
- Care-avoidant illness anxiety delaying presentation of true medical disease (e.g. ignored red-flag cancer or cardiac symptoms)
- Severe depression or functional collapse driven by disease conviction — escalate intensity of care
- Near-delusional disease conviction with secondary depression — treat health-anxiety pathway (CBT/SSRI) while excluding primary psychosis
- Iatrogenic harm from endless uncoordinated investigations reinforcing threat beliefs without new clinical change
- High ED/primary-care utilisation with doctor-shopping and ruptured therapeutic alliances
Meet the patient
He is 37, an engineer, and he has brought a spreadsheet. Column A is the date; column B is the symptom; column C is the search term; column D is what he decided it was. The most frequent entry in column D is motor neuron disease.[9][12]
He has had two normal neurology reviews and an MRI he describes as "probably read too quickly." He is not deluded, he is not lying, and he is exhausted. His wife has stopped answering the question "does this twitch look normal to you?"[9][10]
The trainee's instinct is to reassure him. That instinct is the illness.[10][1]
References20ShowHide
- [1]Barsky AJ, Ahern DK Cognitive behavior therapy for hypochondriasis: a randomized controlled trial JAMA, 2004.PMID 15039413
- [2]Greeven A, van Balkom AJ, Visser S, et al. Cognitive behavior therapy and paroxetine in the treatment of hypochondriasis: a randomized controlled trial Am J Psychiatry, 2007.PMID 17202549
- [3]Tyrer P, Cooper S, Salkovskis P, et al. Clinical and cost-effectiveness of cognitive behaviour therapy for health anxiety in medical patients: a multicentre randomised controlled trial Lancet, 2014.PMID 24139977
- [4]Fallon BA, Ahern DK, Pavlicova M, et al. A Randomized Controlled Trial of Medication and Cognitive-Behavioral Therapy for Hypochondriasis Am J Psychiatry, 2017.PMID 28659038
- [5]Fallon BA, Petkova E, Skritskaya N, et al. A double-masked, placebo-controlled study of fluoxetine for hypochondriasis J Clin Psychopharmacol, 2008.PMID 19011432
- [6]Olatunji BO, Kauffman BY, Meltzer S, et al. Cognitive-behavioral therapy for hypochondriasis/health anxiety: a meta-analysis of treatment outcome and moderators Behav Res Ther, 2014.PMID 24954212
- [7]Hedman E, Andersson G, Andersson E, et al. Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial Br J Psychiatry, 2011.PMID 21357882
- [8]Axelsson E, Andersson E, Ljótsson B, et al. Effect of Internet vs Face-to-Face Cognitive Behavior Therapy for Health Anxiety: A Randomized Noninferiority Clinical Trial JAMA Psychiatry, 2020.PMID 32401286
- [9]Warwick HM, Salkovskis PM Hypochondriasis Behav Res Ther, 1990.PMID 2183757
- [10]Salkovskis PM, Warwick HM Morbid preoccupations, health anxiety and reassurance: a cognitive-behavioural approach to hypochondriasis Behav Res Ther, 1986.PMID 3753387
- [11]Sunderland M, Newby JM, Andrews G Health anxiety in Australia: prevalence, comorbidity, disability and service use Br J Psychiatry, 2013.PMID 22500013
- [12]Tyrer P, Cooper S, Crawford M, et al. Prevalence of health anxiety problems in medical clinics J Psychosom Res, 2011.PMID 22118381
- [13]Mataix-Cols D, Isomura K, Sidorchuk A, et al. All-Cause and Cause-Specific Mortality Among Individuals With Hypochondriasis JAMA Psychiatry, 2024.PMID 38091000
- [14]Dimsdale JE, Creed F, Escobar J, et al. Somatic symptom disorder: an important change in DSM J Psychosom Res, 2013.PMID 23972410
- [15]Dimsdale JE, Levenson J What's next for somatic symptom disorder? Am J Psychiatry, 2013.PMID 24306336
- [16]Mayou R Is the DSM-5 chapter on somatic symptom disorder any better than DSM-IV somatoform disorder? Br J Psychiatry, 2014.PMID 25029686
- [17]Tyrer P, Salkovskis P, Tyrer H, et al. Cognitive-behaviour therapy for health anxiety in medical patients (CHAMP): a randomised controlled trial with outcomes to 5 years Health Technol Assess, 2017.PMID 28877841
- [18]Cooper K, Gregory JD, Walker I, et al. Cognitive Behaviour Therapy for Health Anxiety: A Systematic Review and Meta-Analysis Behav Cogn Psychother, 2017.PMID 28229805
- [19]Kroenke K, Spitzer RL, Williams JB The PHQ-15: validity of a new measure for evaluating the severity of somatic symptoms Psychosom Med, 2002.PMID 11914441
- [20]Greeven A, van Balkom AJ, van der Leeden R, et al. Cognitive behavioral therapy versus paroxetine in the treatment of hypochondriasis: an 18-month naturalistic follow-up J Behav Ther Exp Psychiatry, 2009.PMID 19616195