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Psych MEQs / SAQsPsychopharmacology — phototherapy and chronotherapy

Psych MEQs / SAQs · Psychopharmacology — phototherapy and chronotherapy

Bright light therapy and chronotherapy for winter depression (MEQ)

FRANZCP-style MEQ on BLT parameters, Can-SAD, safety, and chronotherapy escalation.

20 marks20 min1 min readVerification in progress

Target exams

FRANZCPMRCPsychABPNMD-DNB
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Target exams

FRANZCPMRCPsychABPNMD-DNB
Prompt
A 29-year-old teacher in southern Australia presents each June–August with major depression featuring hypersomnia, carbohydrate craving, and anergy, remitting by October for three consecutive years. No prior mania. PHQ-9 is 18; passive suicidal ideation without plan. She wants to avoid medication if possible but will consider an SSRI. (i) Define seasonal pattern and justify bright light therapy as a first-line option. (ii) Prescribe a concrete BLT protocol (device, lux, duration, timing, technique). (iii) Compare with fluoxetine using Can-SAD-level evidence. (iv) List key adverse effects and hard stop rules including hypomania and ocular red flags. (v) Outline when you would add wake therapy/chronotherapy packages or escalate beyond light. (20 marks)

Model answer

Reveal model answerShowHide

(i) Seasonal pattern and light as first-line. DSM-style seasonal pattern: regular temporal relationship between major depressive episodes and a particular time of year (here winter) across successive years, with full remissions at other times. Her reverse-vegetative features match the classic winter SAD phenotype described since Rosenthal. Meta-analyses (Golden; Pjrek) support bright light therapy efficacy for SAD; it is an appropriate first-line non-drug option given preference and moderate severity without active plan.[1][2][6]

(ii) Protocol. UV-filtered commercial light box delivering approximately 10,000 lux at the manufacturer’s prescribed distance; about 30 minutes daily shortly after habitual waking; eyes open facing toward the box while reading/working (not staring); continue through the symptomatic winter months; early review for tolerability then efficacy at 1–3 weeks. Avoid late-evening sessions.[3]

(iii) Versus fluoxetine. Can-SAD found light therapy and fluoxetine 20 mg oral daily comparably effective for winter SAD, with light often showing earlier response onset and a different AE profile. Offer either; combine if incomplete response or strong dual preference after discussion.[4]

(iv) Safety. Common: headache, eye strain, nausea, irritability, insomnia if mistimed. Hard stops: emergent hypomania/mania (stop/reduce light, reassess bipolar spectrum); ocular disease or severe photophobia (pause, ophthalmic review); photosensitising drugs without review. Always maintain suicide risk assessment — seasonality is not reassurance.[3]

(v) Escalation. If severity rises (active SI, psychosis, poor intake), escalate care intensity; do not rely on light alone. Specialist chronotherapy packages (wake therapy with light ± medication) are for structured settings when rapid response is needed. Incomplete winter response after adequate BLT: optimise timing/dose, add SSRI, consider CBT-SAD skills for durability.[5][7]

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References7ShowHide
  1. [1]Rosenthal NE, Sack DA, Gillin JC, et al. Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy. Arch Gen Psychiatry, 1984.PMID 6581756
  2. [2]Golden RN, Gaynes BN, Ekstrom RD, et al. The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. Am J Psychiatry, 2005.PMID 15800134
  3. [3]Terman M, Terman JS. Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects. CNS Spectr, 2005.PMID 16041296
  4. [4]Lam RW, Levitt AJ, Levitan RD, et al. The Can-SAD study: a randomized controlled trial of the effectiveness of light therapy and fluoxetine in patients with winter seasonal affective disorder. Am J Psychiatry, 2006.PMID 16648320
  5. [5]Wirz-Justice A, Benedetti F, Berger M, et al. Chronotherapeutics (light and wake therapy) in affective disorders. Psychol Med, 2005.PMID 16045060
  6. [6]Pjrek E, Friedrich ME, Cambioli L, et al. The Efficacy of Light Therapy in the Treatment of Seasonal Affective Disorder: A Meta-Analysis of Randomized Controlled Trials. Psychother Psychosom, 2020.PMID 31574513
  7. [7]Benedetti F, Riccaboni R, Locatelli C, et al. Rapid treatment response of suicidal symptoms to lithium, sleep deprivation and light therapy (chronotherapeutics) in drug-resistant bipolar depression. J Clin Psychiatry, 2014.PMID 24345382
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