Choosing bupropion after SSRI sexual dysfunction (CASC)

Station instructions (candidate)

You have 7 minutes. Explore goals: mood recovery, sexual function, smoking, weight concerns. Explain that sertraline-related sexual dysfunction is common and treatable by strategy, not shame. Offer a collaborative plan that may include switching to or adding bupropion after screening for seizure risk factors, with a clear oral dose plan and early review. Contrast honestly with mirtazapine (helpful for sleep/appetite; sedation and weight gain trade-offs). Do not claim zero seizure risk. Do not start venlafaxine+mirtazapine tonight as casual "rocket fuel." Do not dismiss online fears.^{[1][3][4][6][7]}