Psych CASC / OSCE · Intellectual disability psychiatry — genetic syndromes
Explain 22q11.2DS psychosis risk and supports to parents — CASC communication station
MRCPsych/FRANZCP-style communication station: explain probabilistic behavioural phenotype and high but not universal psychosis risk in 22q11.2DS, balance hope with vigilance, outline supports and when to seek help.
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Study tools
Target exams
FRANZCPMRCPsychABPNMD-DNB
Prompt
Parents of a 16-year-old with confirmed 22q11.2 deletion syndrome, repaired cardiac disease and mild intellectual disability want a plain-language explanation of mental health risks, early signs of psychosis, what monitoring looks like, and whether this means 'schizophrenia is inevitable'.
Station brief
Format. Communication station, approximately 7–10 minutes. You are the psychiatry registrar in the adolescent neurodevelopmental / ID clinic. [3]
Candidate instructions. Explain what 22q11.2 deletion means for mental health, address whether schizophrenia is inevitable, describe other common psychiatric issues, outline monitoring and when to seek urgent help, and check understanding with empathy. The examiner plays both parents. [2][3]
References5ShowHide
- [1]Murphy KC, Jones LA, Owen MJ High rates of schizophrenia in adults with velo-cardio-facial syndrome Arch Gen Psychiatry, 1999.PMID 10530637
- [2]Schneider M, Debbané M, Bassett AS, et al. Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome Am J Psychiatry, 2014.PMID 24577245
- [3]Bassett AS, McDonald-McGinn DM, Devriendt K, et al. Practical guidelines for managing patients with 22q11.2 deletion syndrome J Pediatr, 2011.PMID 21570089
- [4]McDonald-McGinn DM, Sullivan KE, Marino B, et al. 22q11.2 deletion syndrome Nat Rev Dis Primers, 2015.PMID 27189754
- [5]Dykens EM Measuring behavioral phenotypes: provocations from the "new genetics" Am J Ment Retard, 1995.PMID 7779347