Phys Vivas · respiratory
Solitary Pulmonary Nodule — Viva Defence
Structured DCE viva for the solitary pulmonary nodule: defence of an incidental 11 mm spiculated nodule in an ex-smoker with emphysema and cardiac comorbidity — surveillance versus biopsy, fitness for surgery, and the multidisciplinary decision.
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Opening statement (SASPOP, delivered aloud)
"Mr Doyle is a 67-year-old ex-smoker with an incidental 11 mm spiculated solid nodule in the right upper lobe, on a background of severe emphysema and significant ischaemic heart disease with impaired ventricular function. His main problems are: a radiologically suspicious nodule whose malignancy probability is high enough that surveillance alone is not defensible; severely limited pulmonary reserve that makes both transthoracic biopsy hazardous and any resection marginal; cardiac comorbidity that compounds procedural risk; and acute anxiety about a possible cancer diagnosis. I would like to establish the nodule's temporal behaviour by finding prior imaging, quantify risk formally, characterise it with PET-CT, obtain tissue by the safest route — which in him is bronchoscopic, not percutaneous — and take every fork of this pathway through the lung nodule MDT with his preferences heard at each step." [1] [2]
References7ShowHide
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- [2]McWilliams A, Tammemagi MC, Mayo JR, et al. Probability of cancer in pulmonary nodules detected on first screening CT N Engl J Med, 2013.PMID 24004118
- [3]Gould MK, Maclean CC, Kuschner WG, et al. Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions: a meta-analysis JAMA, 2001.PMID 11180735
- [4]Wiener RS, Schwartz LM, Woloshin S, et al. Population-based risk for complications after transthoracic needle lung biopsy of a pulmonary nodule: an analysis of discharge records Ann Intern Med, 2011.PMID 21810706
- [5]Folch EE, Pritchett MA, Nead MA, et al. Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: One-Year Results of the Prospective, Multicenter NAVIGATE Study J Thorac Oncol, 2019.PMID 30476574
- [6]Callister ME, Baldwin DR, Akram AR, et al. British Thoracic Society guidelines for the investigation and management of pulmonary nodules Thorax, 2015.PMID 26082159
- [7]Saji H, Okada M, Tsuboi M, et al. Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial Lancet, 2022.PMID 35461558